Muscle contraction and force: the importance of an ancillary network, nutrient supply and waste removal

TY - JOUR

T1 - Muscle contraction and force

T2 - the importance of an ancillary network, nutrient supply and waste removal

AU - Brüggemann, Dagmar Adeline

AU - Risbo, Jens

AU - Pierzynowski, Stefan G.

AU - Harrison, Adrian Paul

PY - 2008

Y1 - 2008

N2 - Muscle contraction studies often focus solely on myofibres and the proteins known to be involved in the processes of sarcomere shortening and cross-bridge cycling, but skeletal muscle also comprises a very elaborate ancillary network of capillaries, which not only play a vital role in terms of nutrient delivery and waste product removal, but are also tethered to surrounding fibres by collagen "wires". This paper therefore addresses aspects of the ancillary network of skeletal muscle at both a microscopic and functional level in order to better understand its role holistically as a considerable contributor to force transfer within muscular tissue.

AB - Muscle contraction studies often focus solely on myofibres and the proteins known to be involved in the processes of sarcomere shortening and cross-bridge cycling, but skeletal muscle also comprises a very elaborate ancillary network of capillaries, which not only play a vital role in terms of nutrient delivery and waste product removal, but are also tethered to surrounding fibres by collagen "wires". This paper therefore addresses aspects of the ancillary network of skeletal muscle at both a microscopic and functional level in order to better understand its role holistically as a considerable contributor to force transfer within muscular tissue.

KW - Former LIFE faculty

KW - Collagen

KW - muscle performance

KW - fatigue

KW - capillary network

U2 - 10.3390/ijms9081472

DO - 10.3390/ijms9081472

M3 - Journal article

C2 - 19325816

SN - 1661-6596

VL - 9

SP - 1472

EP - 1488

JO - International Journal of Molecular Sciences (Online)

JF - International Journal of Molecular Sciences (Online)

ER -