Multimodality treatment approach in children with cerebral arteriovenous malformation-a survey in the Danish population

TY - JOUR

T1 - Multimodality treatment approach in children with cerebral arteriovenous malformation-a survey in the Danish population

AU - Skjøth-Rasmussen, Jane

AU - Obbekjær, Tina

AU - Birkeland, Peter

AU - Hauerberg, John

AU - Juhler, Marianne

PY - 2012/4

Y1 - 2012/4

N2 - INTRODUCTION: Arteriovenous malformations are not a common disease in childhood. A national survey was conducted to reveal the Danish incidence of the disease, presentation, choice of treatment, and outcome. MATERIALS AND METHODS: Forty patients were admitted to any of the five neurosurgical centers during the years 2000-2008. A retrospective survey was conducted using hospital records. RESULTS: Twenty-three males and 17 females presented with AVM with a mean age of 11.3 (1 month-18 years). The incidence was found to be 0.4/100,000. Early fatal outcome was seen in three patients. Treatment was surgery (12), endovascular (5), radiosurgery (6), or a combination of the above (10). Four patients were treated conservatively. Complications of the treatment were seen in 27%. Occlusion rate was 74%. Good or excellent outcome was seen in 65%. CONCLUSION: A national survey may give a lower rate of success than in the specialized centers accepting patients more eligible for treatment. Still, the low number of children could call for centralization and collaboration in this population.

AB - INTRODUCTION: Arteriovenous malformations are not a common disease in childhood. A national survey was conducted to reveal the Danish incidence of the disease, presentation, choice of treatment, and outcome. MATERIALS AND METHODS: Forty patients were admitted to any of the five neurosurgical centers during the years 2000-2008. A retrospective survey was conducted using hospital records. RESULTS: Twenty-three males and 17 females presented with AVM with a mean age of 11.3 (1 month-18 years). The incidence was found to be 0.4/100,000. Early fatal outcome was seen in three patients. Treatment was surgery (12), endovascular (5), radiosurgery (6), or a combination of the above (10). Four patients were treated conservatively. Complications of the treatment were seen in 27%. Occlusion rate was 74%. Good or excellent outcome was seen in 65%. CONCLUSION: A national survey may give a lower rate of success than in the specialized centers accepting patients more eligible for treatment. Still, the low number of children could call for centralization and collaboration in this population.

U2 - 10.1007/s00381-011-1640-5

DO - 10.1007/s00381-011-1640-5

M3 - Journal article

C2 - 22160476

SN - 0256-7040

SP - 587

EP - 592

JO - Child's Nervous System

JF - Child's Nervous System

ER -