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Mucin dispersions as a model for the oromucosal mucus layer in in vitro and ex vivo buccal permeability studies of small molecules
Eva Marxen, Mette Dalskov Mosgaard,
Anne Marie Lynge Pedersen
,
Jette Jacobsen
11
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Keyphrases
Small Molecules
100%
Permeability Studies
100%
Buccal Permeability
100%
Oromucosal
100%
Mucus Layer
100%
Mucin
100%
Incubation
50%
Nicotine
50%
Mannitol
33%
Porcine Gastric mucin
33%
Propranolol
33%
Caffeine
33%
Per Se
16%
Tissue Integrity
16%
Oral mucosa
16%
Porcine Buccal mucosa
16%
Permeability Model
16%
Epithelium
16%
Drug Permeation
16%
Drug Diffusion
16%
TR146 Cells
16%
Biochemistry, Genetics and Molecular Biology
Small Molecule
100%
Mucin
100%
Dispersion
100%
Pig
37%
Mannitol
25%
Propranolol
25%
Drug Diffusion
12%
Buccal Mucosa
12%
Mouth Mucosa
12%
Pharmacology, Toxicology and Pharmaceutical Science
Mucin
100%
Pig
50%
Stomach Mucin
33%
Propranolol
33%
Mannitol
33%