Molluscicidal saponins from Phytolacca dodecandra

S. T. Thiilborg; S. B. Christensen; Claus Cornett; C. E. Olsen; E. Lemmich

Molluscicidal saponins from Phytolacca dodecandra

S. T. Thiilborg, S. B. Christensen, Claus Cornett, C. E. Olsen, E. Lemmich

21 Citationer (Scopus)

Abstract

Two new monodesmosidic saponins were isolated from an aqueous extract of the Ethiopian strain 44 of Phytolacca dodecandra. Their structures were established as 3-0-alpha-L-rhamnopyranosyl-(1-->2)-O-[beta-D-galactopyranosyl-(1-->3)] -beta-D-glucopyranosyloleanolic acid and 3-O-beta-D-xylopyranosyl-(1-->6)-O-beta-D-gluco-pyranosyl-(1-->3)]-beta -D-glucopyranosyloleanolic acid mainly by spectroscopic methods (LSIMS, H-1 NMR, COSY, NOESY, TOCSY, J-resolved H-1 NMR, C-13 NMR, HETCOR). The saponins are potent molluscicides against the schistosomiasis transmitting snail Biomphalaria glabrata with LC50 values of 2 and 5 ppm, respectively.

Originalsprog	Udefineret/Ukendt
Tidsskrift	Phytochemistry
Vol/bind	32
Udgave nummer	5
Sider (fra-til)	1167-1171
Antal sider	5
ISSN	0031-9422
Status	Udgivet - 1993

Emneord

phytolacca-dodecandra phytolaccaceae endod strain 44 endod-s molluscicides triterpenoid saponins oleanolic acid lherit

Citationsformater

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title = "Molluscicidal saponins from Phytolacca dodecandra",

abstract = "Two new monodesmosidic saponins were isolated from an aqueous extract of the Ethiopian strain 44 of Phytolacca dodecandra. Their structures were established as 3-0-alpha-L-rhamnopyranosyl-(1-->2)-O-[beta-D-galactopyranosyl-(1-->3)] -beta-D-glucopyranosyloleanolic acid and 3-O-beta-D-xylopyranosyl-(1-->6)-O-beta-D-gluco-pyranosyl-(1-->3)]-beta -D-glucopyranosyloleanolic acid mainly by spectroscopic methods (LSIMS, H-1 NMR, COSY, NOESY, TOCSY, J-resolved H-1 NMR, C-13 NMR, HETCOR). The saponins are potent molluscicides against the schistosomiasis transmitting snail Biomphalaria glabrata with LC50 values of 2 and 5 ppm, respectively.",

keywords = "phytolacca-dodecandra phytolaccaceae endod strain 44 endod-s molluscicides triterpenoid saponins oleanolic acid lherit",

author = "Thiilborg, {S. T.} and Christensen, {S. B.} and Claus Cornett and Olsen, {C. E.} and E. Lemmich",

year = "1993",

language = "Udefineret/Ukendt",

volume = "32",

pages = "1167--1171",

journal = "Phytochemistry",

issn = "0031-9422",

publisher = "Pergamon Press",

number = "5",

}

TY - JOUR

T1 - Molluscicidal saponins from Phytolacca dodecandra

AU - Thiilborg, S. T.

AU - Christensen, S. B.

AU - Cornett, Claus

AU - Olsen, C. E.

AU - Lemmich, E.

PY - 1993

Y1 - 1993

N2 - Two new monodesmosidic saponins were isolated from an aqueous extract of the Ethiopian strain 44 of Phytolacca dodecandra. Their structures were established as 3-0-alpha-L-rhamnopyranosyl-(1-->2)-O-[beta-D-galactopyranosyl-(1-->3)] -beta-D-glucopyranosyloleanolic acid and 3-O-beta-D-xylopyranosyl-(1-->6)-O-beta-D-gluco-pyranosyl-(1-->3)]-beta -D-glucopyranosyloleanolic acid mainly by spectroscopic methods (LSIMS, H-1 NMR, COSY, NOESY, TOCSY, J-resolved H-1 NMR, C-13 NMR, HETCOR). The saponins are potent molluscicides against the schistosomiasis transmitting snail Biomphalaria glabrata with LC50 values of 2 and 5 ppm, respectively.

AB - Two new monodesmosidic saponins were isolated from an aqueous extract of the Ethiopian strain 44 of Phytolacca dodecandra. Their structures were established as 3-0-alpha-L-rhamnopyranosyl-(1-->2)-O-[beta-D-galactopyranosyl-(1-->3)] -beta-D-glucopyranosyloleanolic acid and 3-O-beta-D-xylopyranosyl-(1-->6)-O-beta-D-gluco-pyranosyl-(1-->3)]-beta -D-glucopyranosyloleanolic acid mainly by spectroscopic methods (LSIMS, H-1 NMR, COSY, NOESY, TOCSY, J-resolved H-1 NMR, C-13 NMR, HETCOR). The saponins are potent molluscicides against the schistosomiasis transmitting snail Biomphalaria glabrata with LC50 values of 2 and 5 ppm, respectively.

KW - phytolacca-dodecandra phytolaccaceae endod strain 44 endod-s molluscicides triterpenoid saponins oleanolic acid lherit

M3 - Tidsskriftartikel

SN - 0031-9422

VL - 32

SP - 1167

EP - 1171

JO - Phytochemistry

JF - Phytochemistry

IS - 5

ER -