TY - JOUR
T1 - Model cell membranes
T2 - discerning lipid and protein contributions in shaping the cell
AU - Günther-Pomorski, Thomas
AU - Nylander, Tommy
AU - Cardenas Gomez, Marite
PY - 2014/3
Y1 - 2014/3
N2 - The high complexity of biological membranes has motivated the development and application of a wide range of model membrane systems to study biochemical and biophysical aspects of membranes in situ under well defined conditions. The aim is to provide fundamental understanding of processes controlled by membrane structure, permeability and curvature as well as membrane proteins by using a wide range of biochemical, biophysical and microscopic techniques. This review gives an overview of some currently used model biomembrane systems. We will also discuss some key membrane protein properties that are relevant for protein-membrane interactions in terms of protein structure and how it is affected by membrane composition, phase behavior and curvature.
AB - The high complexity of biological membranes has motivated the development and application of a wide range of model membrane systems to study biochemical and biophysical aspects of membranes in situ under well defined conditions. The aim is to provide fundamental understanding of processes controlled by membrane structure, permeability and curvature as well as membrane proteins by using a wide range of biochemical, biophysical and microscopic techniques. This review gives an overview of some currently used model biomembrane systems. We will also discuss some key membrane protein properties that are relevant for protein-membrane interactions in terms of protein structure and how it is affected by membrane composition, phase behavior and curvature.
UR - http://www.scopus.com/inward/record.url?scp=84887669524&partnerID=8YFLogxK
U2 - 10.1016/j.cis.2013.10.028
DO - 10.1016/j.cis.2013.10.028
M3 - Journal article
C2 - 24268587
SN - 0001-8686
VL - 205
SP - 207
EP - 220
JO - Advances in Colloid and Interface Science
JF - Advances in Colloid and Interface Science
ER -