Methylation-associated Silencing of microRNA-126 and its Host Gene EGFL7 in Malignant Pleural Mesothelioma

Medicin og biovidenskab

• Malignant Mesothelioma 100%
• Epidermal Growth Factor 80%
• Methylation 74%
• MicroRNAs 69%
• Pleura 42%
• Genes 33%
• Biopsy 11%
• CpG Islands 11%
• Messenger RNA 10%
• Genetic Promoter Regions 8%
• Introns 8%
• High-Throughput Nucleotide Sequencing 8%
• Formaldehyde 8%
• Paraffin 8%
• Epigenomics 7%
• Histology 7%
• Sensitivity and Specificity 6%
• Down-Regulation 6%
• Polymerase Chain Reaction 5%
• DNA 5%
• Survival 5%
• Therapeutics 1%