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Methodology for Accurate Detection of Mitochondrial DNA Methylation
Mie Mechta, Lars Roed Ingerslev,
Romain Barrès
4
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Keyphrases
Detection Accuracy
100%
Mitochondrial DNA
100%
Bisulfite Sequencing
100%
5-hydroxymethylcytosine (5hmC)
60%
Single-stranded DNA (ssDNA)
40%
Secondary Structure
40%
Single-base Resolution
20%
DNA Quantification
20%
Sodium Bisulfite
20%
Nuclear DNA (nDNA)
20%
BamHI
20%
Bisulfite
20%
Whole Genome
20%
Tertiary Structure
20%
Denaturation
20%
Sequencing Artifacts
20%
DNA Context
20%
Nuclear Genome
20%
Cytosine
20%
Accurate Quantification
20%
Absolute Quantification
20%
Bioinformatics pipeline
20%
Enzymatic Digestion
20%
DNA Methylation (DNAm)
20%
Uracil
20%
Sequence Method
20%
Methylation Status
20%
Biochemistry, Genetics and Molecular Biology
Mitochondrial DNA
100%
DNA Methylation
100%
Bisulfite Sequencing
83%
Cytosine
66%
Methylation
50%
Bisulfite
33%
Single-Stranded DNA
33%
Denaturation
16%
Tertiary Structure
16%
Bioinformatics
16%
Uracil
16%
BamHI
16%
Nuclear DNA
16%
Protein Secondary Structure
16%