Metformin og obstetriske patienter

Katrine Dahl Pedersen, Nathalie Søderhamn Bülow, Kasper Aaboe, Julie Galsgaard, Helle Sand Odgaard, Elisabeth Reinhardt Mathiesen, Jeannet Lauenborg

1 Citationer (Scopus)

Abstract

Polycystic ovary syndrome (PCOS) is associated with insulin resistance, infertility, obesity and gestational complications. Metformin is widely used in fertility treatment of women with PCOS, due to a suggested positive effect of continued metformin treatment beyond the first trimester on pregnancy complications. Larger randomized trials have failed to confirm this. Metformin treatment has not been found to be superior to insulin treatment in women with gestational diabetes and may be associated with long-term consequences in the children in the form of overweight and disturbed glucose metabolism.

Bidragets oversatte titelMetformin and the obstetric patient
OriginalsprogDansk
ArtikelnummerV05150438
TidsskriftUgeskrift for Laeger
Vol/bind177
Antal sider4
ISSN0041-5782
StatusUdgivet - 7 dec. 2015

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