Markers of metabolic health in children differ between weekdays - the result of unhealthier weekend behavior

TY - JOUR

T1 - Markers of metabolic health in children differ between weekdays - the result of unhealthier weekend behavior

AU - Hjorth, Mads Fiil

AU - Damsgaard, Camilla Trab

AU - Michaelsen, Kim F.

AU - Astrup, Arne

AU - Sjödin, Anders Mikael

N1 - CURIS 2015 NEXS 088

PY - 2015/4/1

Y1 - 2015/4/1

N2 - Objective The aim of this study was to investigate whether indicators of metabolic health fluctuate during the week in a group of children posing unhealthier physical activity, sedentary time, and sleep during weekends compared to weekdays. Methods A total of 807 eight- to eleven-year-old children had valid metabolic health markers from one, two, or three measurements contributing 2190 to 2240 observations of metabolic health markers. The weekly variation was tested using linear mixed models. Results Homeostatic model assessment of insulin resistance (HOMAIR), triglycerides, leptin (all P < 0.001), and adiponectin (P = 0.03) decreased from Monday to Friday, whereas ghrelin increased (P < 0.001). HOMAIR, triglycerides, and leptin were 35%, 28%, and 33% higher on Mondays compared to Fridays, respectively, and ghrelin was 7% lower on Mondays compared to Fridays (all P < 0.001). Conclusions The large weekly variation in HOMAIR, triglycerides, and leptin was likely the result of unhealthier behaviors during weekends. These findings have public health relevance and raise methodological issues that should ideally be taken into account in future studies.

AB - Objective The aim of this study was to investigate whether indicators of metabolic health fluctuate during the week in a group of children posing unhealthier physical activity, sedentary time, and sleep during weekends compared to weekdays. Methods A total of 807 eight- to eleven-year-old children had valid metabolic health markers from one, two, or three measurements contributing 2190 to 2240 observations of metabolic health markers. The weekly variation was tested using linear mixed models. Results Homeostatic model assessment of insulin resistance (HOMAIR), triglycerides, leptin (all P < 0.001), and adiponectin (P = 0.03) decreased from Monday to Friday, whereas ghrelin increased (P < 0.001). HOMAIR, triglycerides, and leptin were 35%, 28%, and 33% higher on Mondays compared to Fridays, respectively, and ghrelin was 7% lower on Mondays compared to Fridays (all P < 0.001). Conclusions The large weekly variation in HOMAIR, triglycerides, and leptin was likely the result of unhealthier behaviors during weekends. These findings have public health relevance and raise methodological issues that should ideally be taken into account in future studies.

U2 - 10.1002/oby.21034

DO - 10.1002/oby.21034

M3 - Journal article

C2 - 25755216

SN - 1930-7381

VL - 23

SP - 733

EP - 736

JO - Obesity

JF - Obesity

IS - 4

ER -