Malaria vaccines: immunity, models and monoclonal antibodies

TY - JOUR

T1 - Malaria vaccines: immunity, models and monoclonal antibodies

AU - Hviid, Lars

AU - Barfod, Lea

PY - 2008

Y1 - 2008

N2 - Although experts in the field have agreed on the malaria vaccine technology roadmap that should be followed (http://www.malariavaccineroadmap.net/), the path towards an effective malaria vaccine remains littered with intellectual and practical pot-holes. The animal models that are currently available are problematic, and current understanding of the exact mechanisms and targets of protective immune responses is incomplete. However, recent technological advances might help overcome some of these hurdles.

AB - Although experts in the field have agreed on the malaria vaccine technology roadmap that should be followed (http://www.malariavaccineroadmap.net/), the path towards an effective malaria vaccine remains littered with intellectual and practical pot-holes. The animal models that are currently available are problematic, and current understanding of the exact mechanisms and targets of protective immune responses is incomplete. However, recent technological advances might help overcome some of these hurdles.

U2 - 10.1016/j.pt.2008.05.007

DO - 10.1016/j.pt.2008.05.007

M3 - Journal article

C2 - 18675589

SN - 1471-4922

VL - 24

SP - 392

EP - 395

JO - Trends in Parasitology

JF - Trends in Parasitology

IS - 9

ER -