Long working hours and cardiovascular disease: a meta-analysis of epidemiologic studies

TY - JOUR

T1 - Long working hours and cardiovascular disease

T2 - a meta-analysis of epidemiologic studies

AU - Kang, Mo-Yeol

AU - Park, Hyunseung

AU - Seo, Jeong-Cheol

AU - Kim, Donghoon

AU - Lim, Youn-Hee

AU - Lim, Sinye

AU - Cho, Soo-Hun

AU - Hong, Yun-Chul

PY - 2012/5

Y1 - 2012/5

N2 - OBJECTIVE: To conduct a meta-analysis from published studies to evaluate the relationship between long working hours and the risk of cardiovascular disease (CVD).METHODS: Among a total of 341 published studies found from publicly accessible databases, five cohort studies and six case-control studies were analyzed for the study.RESULTS: Statistically significant heterogeneity has been observed (P = 0.037). The effect of longer working hours was significantly associated with the risk of CVD in the random-effects model of all 11 studies (odds ratio, 1.37; 95% confidence interval, 1.11 to 1.70). On the basis of meta-regression analysis, the result was not affected by the mean age, region, or the study year. The P value using Eager test was 0.701 suggesting this analysis was unlikely to have any publication bias.CONCLUSIONS: These findings provide evidence of increased CVD with long working hours.

AB - OBJECTIVE: To conduct a meta-analysis from published studies to evaluate the relationship between long working hours and the risk of cardiovascular disease (CVD).METHODS: Among a total of 341 published studies found from publicly accessible databases, five cohort studies and six case-control studies were analyzed for the study.RESULTS: Statistically significant heterogeneity has been observed (P = 0.037). The effect of longer working hours was significantly associated with the risk of CVD in the random-effects model of all 11 studies (odds ratio, 1.37; 95% confidence interval, 1.11 to 1.70). On the basis of meta-regression analysis, the result was not affected by the mean age, region, or the study year. The P value using Eager test was 0.701 suggesting this analysis was unlikely to have any publication bias.CONCLUSIONS: These findings provide evidence of increased CVD with long working hours.

KW - Adult

KW - Aged

KW - Cardiovascular Diseases/epidemiology

KW - Confidence Intervals

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Odds Ratio

KW - Time Factors

KW - Work Schedule Tolerance/physiology

KW - Young Adult

U2 - 10.1097/JOM.0b013e31824fe192

DO - 10.1097/JOM.0b013e31824fe192

M3 - Journal article

C2 - 22576460

SN - 1076-2752

VL - 54

SP - 532

EP - 537

JO - Journal of Occupational and Environmental Medicine

JF - Journal of Occupational and Environmental Medicine

IS - 5

ER -