Long-term treatment of nocturnal enuresis with desmopressin. A follow-up study

TY - JOUR

T1 - Long-term treatment of nocturnal enuresis with desmopressin. A follow-up study

AU - Knudsen, U B

AU - Rittig, Søren

AU - Nørgaard, J P

AU - Banner, Jytte

AU - Pedersen, E B

AU - Djurhuus, Jens Christian

PY - 1991

Y1 - 1991

N2 - Eight patients with monosymptomatic nocturnal enuresis (age 11-24 years) were investigated prior to and after 24 weeks of desmopressin treatment in order to evaluate the impact on the endogenous vasopressin secretion and urinary output. No effect on plasma vasopressin, diurnal urinary volume, and urinary osmolality were found after this long-term treatment. Overall no changes in either body weight, blood pressure, or hematological variables were demonstrated. This supports previous findings that the treatment appears to be well tolerated and free of side effects in longer term.

AB - Eight patients with monosymptomatic nocturnal enuresis (age 11-24 years) were investigated prior to and after 24 weeks of desmopressin treatment in order to evaluate the impact on the endogenous vasopressin secretion and urinary output. No effect on plasma vasopressin, diurnal urinary volume, and urinary osmolality were found after this long-term treatment. Overall no changes in either body weight, blood pressure, or hematological variables were demonstrated. This supports previous findings that the treatment appears to be well tolerated and free of side effects in longer term.

KW - Adolescent

KW - Circadian Rhythm

KW - Deamino Arginine Vasopressin

KW - Enuresis

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Time Factors

KW - Urine

KW - Vasopressins

M3 - Journal article

C2 - 1926658

SN - 0300-5623

VL - 19

SP - 237

EP - 240

JO - Urological Research

JF - Urological Research

IS - 4

ER -