Large-scale studies of the Leu72Met polymorphism of the ghrelin gene in relation to the metabolic syndrome and associated quantitative traits

TY - JOUR

T1 - Large-scale studies of the Leu72Met polymorphism of the ghrelin gene in relation to the metabolic syndrome and associated quantitative traits

AU - Bing, C

AU - Ambye, L

AU - Fenger, M

AU - Jørgensen, T

AU - Borch-Johnsen, K

AU - Madsbad, S

AU - Urhammer, S

AU - Urhammer, S A

PY - 2005

Y1 - 2005

N2 - Recently, low-frequency polymorphisms in the coding region of the ghrelin gene were suggested to be involved in the aetiology of obesity and to modulate glucose-induced insulin secretion in different ethnic study groups. The objective of the present large study was to investigate whether the Leu72Met polymorphism of the ghrelin gene associates with features of the metabolic syndrome (MS) in the Danish population.

AB - Recently, low-frequency polymorphisms in the coding region of the ghrelin gene were suggested to be involved in the aetiology of obesity and to modulate glucose-induced insulin secretion in different ethnic study groups. The objective of the present large study was to investigate whether the Leu72Met polymorphism of the ghrelin gene associates with features of the metabolic syndrome (MS) in the Danish population.

U2 - 10.1111/j.1464-5491.2005.01575.x

DO - 10.1111/j.1464-5491.2005.01575.x

M3 - Journal article

C2 - 16108842

SN - 0742-3071

VL - 22

SP - 1157

EP - 1160

JO - Diabetic Medicine

JF - Diabetic Medicine

IS - 9

ER -