Large-scale studies of the HphI insulin gene variable-number-of-tandem-repeats polymorphism in relation to Type 2 diabetes mellitus and insulin release

TY - JOUR

T1 - Large-scale studies of the HphI insulin gene variable-number-of-tandem-repeats polymorphism in relation to Type 2 diabetes mellitus and insulin release

AU - Hansen, S K

AU - Gjesing, A P

AU - Rasmussen, S K

AU - Glümer, C

AU - Urhammer, S A

AU - Andersen, G

AU - Rose, C S

AU - Drivsholm, Thomas Bo

AU - Torekov, Signe Sørensen

AU - Jensen, D P

AU - Ekstrøm, C T

AU - Borch-Johnsen, K

AU - Jørgensen, T

AU - Nymark, Christopher Mccarthy

AU - Hansen, T

AU - Pedersen, O

PY - 2004/6/1

Y1 - 2004/6/1

N2 - The class III allele of the variable-number-of-tandem-repeats polymorphism located 5' of the insulin gene (INS-VNTR) has been associated with Type 2 diabetes and altered birthweight. It has also been suggested, although inconsistently, that the class III allele plays a role in glucose-induced insulin response among NGT individuals.

AB - The class III allele of the variable-number-of-tandem-repeats polymorphism located 5' of the insulin gene (INS-VNTR) has been associated with Type 2 diabetes and altered birthweight. It has also been suggested, although inconsistently, that the class III allele plays a role in glucose-induced insulin response among NGT individuals.

U2 - 10.1007/s00125-004-1418-3

DO - 10.1007/s00125-004-1418-3

M3 - Journal article

C2 - 15170498

SN - 0012-186X

VL - 47

SP - 1079

EP - 1087

JO - Diabetologia

JF - Diabetologia

IS - 6

ER -