Keyphrases
ATP Binding Cassette Subfamily B Member 1 (ABCB1)
100%
Pharmacokinetics
100%
Genetic Association
100%
Organic Cation Transporter
100%
Morphine
100%
Pharmacodynamics
71%
Cold Pressor Test
28%
Genetic Variants
28%
Healthy Volunteers
28%
Volume of Distribution
28%
Mechanical Stimulation
14%
Pain Stimulation
14%
Genotype
14%
Morphine-3-glucuronide
14%
P-glycoprotein (P-gp)
14%
Inter-individual Variation
14%
Drug Transporters
14%
Area under the Concentration-time Curve
14%
Morphine-6-glucuronide
14%
Methodological Limitations
14%
Randomized Crossover Trial
14%
Single nucleotide Polymorphism
14%
Non-associated
14%
Plasma Concentration
14%
NONMEM
14%
Tonic
14%
Pharmacokinetic Data
14%
Rectum
14%
Genetic Polymorphism
14%
Cold Water
14%
Antinociceptive
14%
Cold Pain
14%
Cmax
14%
Pain Threshold
14%
Pharmacology, Toxicology and Pharmaceutical Science
Morphine
100%
Pharmacokinetic
100%
Organic Cation Transporter
100%
Pharmacodynamics
71%
Normal Human
42%
Hypertensive Factor
28%
Volume of Distribution
28%
Morphine 3 Glucuronide
14%
Effusion
14%
Glycoprotein
14%
NONMEM
14%
Morphine 6 Glucuronide
14%
Agricultural and Biological Sciences
Pharmacokinetic
100%
Uridine Diphosphate
100%
Genetic Divergence
28%
Blood Plasma
28%
Morphine-6-Glucuronide
14%
Morphine-3-Glucuronide
14%
Rectum
14%
Single Nucleotide Polymorphism
14%
Genetic Polymorphism
14%
Neuroscience
Organic Cation Transporter
100%
Glucuronosyltransferase 2B7
100%
Biochemistry, Genetics and Molecular Biology
Morphine-6-Glucuronide
14%
Plasma Concentration-Time Curve
14%
Morphine-3-Glucuronide
14%
Maximum Plasma Concentration
14%