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Kinase-Centric Computational Drug Development
Albert J. Kooistra
, Andrea Volkamer
*
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Corresponding author af dette arbejde
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Keyphrases
Sequence Data
100%
Structure Data
100%
Sequence Structure
100%
Bioactivity Data
100%
Drug Target
50%
Protein Family
50%
Unmet Needs
50%
Illustrative Examples
50%
Mutation Data
50%
Dysregulation
50%
Machine Learning Techniques
50%
Binding Site Prediction
50%
Single Structure
50%
Structure-activity
50%
Cancer-related Inflammation
50%
Protein-ligand Interaction
50%
Druggable Proteins
50%
Fingerprinting
50%
Structure Analysis
50%
Kinase Drugs
50%
Cellular Processes
50%
Drug Design
50%
Activity Prediction
50%
Large Pools
50%
Sequence Comparison
50%
Autoimmune Disease
50%
Sequence mutation
50%
Pharmacology, Toxicology and Pharmaceutical Science
Drug Development
100%
Phosphotransferase
100%
Autoimmune Disease
25%
Phosphotransferase Inhibitor
25%
Diseases
25%
Inflammation
25%
Malignant Neoplasm
25%
Cellular Processes
25%
Binding Site
25%
Biochemistry, Genetics and Molecular Biology
Kinase
100%
Phosphotransferase
100%
Biological Activity
40%
Binding Site
20%
Structure Analysis
20%
Protein Family
20%