Is there a risk of active sensitization to PPD by patch testing the general population?

Jacob Pontoppidan Thyssen; Torkil Menné; Niels Henrik Nielsen; Allan Linneberg

doi:10.1111/j.1600-0536.2007.01093.x

Is there a risk of active sensitization to PPD by patch testing the general population?

Jacob Pontoppidan Thyssen, Torkil Menné, Niels Henrik Nielsen, Allan Linneberg

12 Citationer (Scopus)

Abstract

Para-phenylenediamine (PPD), a constituent of permanent hair dyes, may cause contact allergy in exposed individuals. It has previously been questioned whether a patch testing with PPD in population-based epidemiological studies is entirely safe. The Glostrup allergy studies patch tested the same cohort twice. In 1990, 567 persons were patch-tested and only one person had a (+) positive reaction to PPD. In 1998, 540 persons were re-invited to a new patch test and 365 (participation rate 68%) were re-tested. There were no positive reactions to PPD. These studies indicate that patch testing with PPD in individuals with no previous positive reactions to PPD or with only one previous positive reaction does not cause active sensitization and can be performed with minimal risk.

Originalsprog	Engelsk
Tidsskrift	Contact Dermatitis
Vol/bind	57
Udgave nummer	2
Sider (fra-til)	133-4
Antal sider	2
ISSN	0105-1873
DOI	https://doi.org/10.1111/j.1600-0536.2007.01093.x
Status	Udgivet - aug. 2007
Udgivet eksternt	Ja

Adgang til dokumentet

10.1111/j.1600-0536.2007.01093.x

Citationsformater

@article{57dda4947fa841b0893819fc7c6b0d43,

title = "Is there a risk of active sensitization to PPD by patch testing the general population?",

abstract = "Para-phenylenediamine (PPD), a constituent of permanent hair dyes, may cause contact allergy in exposed individuals. It has previously been questioned whether a patch testing with PPD in population-based epidemiological studies is entirely safe. The Glostrup allergy studies patch tested the same cohort twice. In 1990, 567 persons were patch-tested and only one person had a (+) positive reaction to PPD. In 1998, 540 persons were re-invited to a new patch test and 365 (participation rate 68%) were re-tested. There were no positive reactions to PPD. These studies indicate that patch testing with PPD in individuals with no previous positive reactions to PPD or with only one previous positive reaction does not cause active sensitization and can be performed with minimal risk.",

keywords = "Allergens, Coloring Agents, Denmark, Dermatitis, Allergic Contact, Humans, Patch Tests, Phenylenediamines, Risk Factors, Journal Article, Research Support, Non-U.S. Gov't",

author = "Thyssen, {Jacob Pontoppidan} and Torkil Menn{\'e} and Nielsen, {Niels Henrik} and Allan Linneberg",

year = "2007",

month = aug,

doi = "10.1111/j.1600-0536.2007.01093.x",

language = "English",

volume = "57",

pages = "133--4",

journal = "Contact Dermatitis",

issn = "0105-1873",