Ionotropic excitatory amino acid receptor ligands. Synthesis and pharmacology of a new amino acid AMPA antagonist

Medicin og biovidenskab

• 2-aminomethylphenylacetic acid 100%
• AMPA Receptors 54%
• Glutamate Receptors 50%
• Ligands 32%
• Pharmacology 30%
• propionic acid 20%
• 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid 18%
• 2-amino-3-cyano-6-methyl-5-(4-pyridyl)pyridine 17%
• alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid 9%
• Second Messenger Systems 8%
• N-Methylaspartate 8%
• N-Methyl-D-Aspartate Receptors 7%
• 2-amino-3-(3-(2-carboxyethyl)-5-methyl-4-isoxazolyl)propionic acid 1%

Kemiske forbindelser

• Excitatory Amino Acid 66%
• Propionic Acid 49%
• AMPA Receptor Agonist 43%
• Antagonist 42%
• AMPA Receptor Antagonist 39%
• N Methyl Dextro Aspartic Acid Receptor Blocking Agent 34%
• Ligand 19%
• Acid 15%
• Agonist 10%
• Compound Isomer 7%
• Time 4%