Intrinsic control of electroresponsive properties of transplanted mammalian brain neurons

TY - JOUR

T1 - Intrinsic control of electroresponsive properties of transplanted mammalian brain neurons

AU - Hounsgaard, J

AU - Yarom, Y

PY - 1985/6/3

Y1 - 1985/6/3

N2 - The present study presents the first analysis of neurons in mammalian brain transplants based on intracellular recording. The results, obtained in brain slices including both donor and host tissue, showed that neuronal precursor cells in embryonic transplants retained their ability to complete their normal differentiation of cell-type-specific electroresponsive properties. Distortions in cell aggregation and synaptic connectivity did not affect this aspect of neuronal differentiation.

AB - The present study presents the first analysis of neurons in mammalian brain transplants based on intracellular recording. The results, obtained in brain slices including both donor and host tissue, showed that neuronal precursor cells in embryonic transplants retained their ability to complete their normal differentiation of cell-type-specific electroresponsive properties. Distortions in cell aggregation and synaptic connectivity did not affect this aspect of neuronal differentiation.

KW - Animals

KW - Cell Differentiation

KW - Cerebellum

KW - Evoked Potentials

KW - Hippocampus

KW - Nerve Tissue

KW - Purkinje Cells

KW - Rats

U2 - 10.1016/0006-8993(85)90497-4

DO - 10.1016/0006-8993(85)90497-4

M3 - Journal article

C2 - 4005567

SN - 0006-8993

VL - 335

SP - 372

EP - 376

JO - Brain Research

JF - Brain Research

IS - 2

ER -