Intracranial Pressure: A Comparison of the Noninvasive HeadSense Monitor versus Lumbar Pressure Measurement

TY - JOUR

T1 - Intracranial Pressure

T2 - A Comparison of the Noninvasive HeadSense Monitor versus Lumbar Pressure Measurement

AU - Hvedstrup, Jeppe

AU - Radojicic, Aleksandra

AU - Moudrous, Walid

AU - Herklots, Martin Willy

AU - Wert, Anton

AU - Holzgraefe, Manfred

AU - Obermann, Mark

AU - Schoonman, Guus G

AU - Jensen, Rigmor Højland

AU - Schytz, Henrik Winther

N1 - Copyright © 2018 Elsevier Inc. All rights reserved.

PY - 2018/4

Y1 - 2018/4

N2 - Objective: To compare a new method of noninvasive intracranial pressure (nICP) measurement with conventional lumbar puncture (LP) opening pressure. Methods: In a prospective multicenter study, patients undergoing LP for diagnostic purposes underwent intracranial pressure measurements with HeadSense, a noninvasive transcranial acoustic device, and indirectly with LP. Noninvasive measurements were conducted with the head in a 30° tilt and in supine position before and after LP. The primary endpoint was the correlation between nICP measurement in supine position before LP and the LP opening pressure. Results: There was no correlation between supine nICPs before LP and the LP opening pressures (r = −0.211, P = 0.358). The 30° head-tilt nICPs correlated with the supine nICPs before LP (r = 0.830, P < 0.01). There was no correlation between supine nICPs before and after LP (r = 0.056, P = 0.831) or between 30° head-tilt nICPs and LP opening pressures (r = −0.038, P = 0.861). Conclusions: There was no correlation between nICPs and LP opening pressures. Further development is warranted before transcranial acoustic HeadSense can become a clinical tool for investigating patients with neurologic conditions.

AB - Objective: To compare a new method of noninvasive intracranial pressure (nICP) measurement with conventional lumbar puncture (LP) opening pressure. Methods: In a prospective multicenter study, patients undergoing LP for diagnostic purposes underwent intracranial pressure measurements with HeadSense, a noninvasive transcranial acoustic device, and indirectly with LP. Noninvasive measurements were conducted with the head in a 30° tilt and in supine position before and after LP. The primary endpoint was the correlation between nICP measurement in supine position before LP and the LP opening pressure. Results: There was no correlation between supine nICPs before LP and the LP opening pressures (r = −0.211, P = 0.358). The 30° head-tilt nICPs correlated with the supine nICPs before LP (r = 0.830, P < 0.01). There was no correlation between supine nICPs before and after LP (r = 0.056, P = 0.831) or between 30° head-tilt nICPs and LP opening pressures (r = −0.038, P = 0.861). Conclusions: There was no correlation between nICPs and LP opening pressures. Further development is warranted before transcranial acoustic HeadSense can become a clinical tool for investigating patients with neurologic conditions.

KW - Adult

KW - Aged

KW - Female

KW - Humans

KW - Intracranial Hypertension/diagnosis

KW - Intracranial Pressure/physiology

KW - Male

KW - Middle Aged

KW - Monitoring, Physiologic/methods

KW - Patient Positioning

KW - Prospective Studies

KW - Spinal Puncture

KW - Young Adult

U2 - 10.1016/j.wneu.2018.01.089

DO - 10.1016/j.wneu.2018.01.089

M3 - Journal article

C2 - 29409948

SN - 1878-8750

VL - 112

SP - e576-e580

JO - World Neurosurgery

JF - World Neurosurgery

ER -