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Inhibitor scaffold for the histone lysine demethylase KDM4C (JMJD2C)
Ulrike Leurs,
Rasmus P Clausen
,
Jesper L Kristensen
,
Brian Lohse
15
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Keyphrases
KDM4C
100%
JMJD2C
100%
Histone Lysine Demethylase
100%
Histone Demethylase
50%
X-linked Mental Retardation
25%
Novel Therapeutics
25%
Epigenetic Regulation
25%
Further Development
25%
Prostate Cancer
25%
Breast Cancer
25%
Oncogene
25%
Therapeutic Approaches
25%
Biological Role
25%
Selective Inhibition
25%
Pharmacology, Toxicology and Pharmaceutical Science
Lysine
100%
Histone
100%
Histone Demethylase
100%
Diseases
50%
Malignant Neoplasm
50%
4 Hydroxypyrazole
50%
Prostate Cancer
50%
Breast Cancer
50%
Biochemistry, Genetics and Molecular Biology
Lysine
100%
Histone
100%
Demethylase
100%
Enzyme
33%
Epigenetics
33%
Oncogene
33%