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Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack
Philip E Morgan, Roger T Dean,
Michael Jonathan Davies
Inflammation, Metabolism and Oxidation
75
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Medicin og biovidenskab
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
8%
Catalytic Domain
5%
Coloring Agents
4%
Coordination Complexes
8%
Edetic Acid
6%
Electron Spin Resonance Spectroscopy
7%
Enzymes
12%
Glutathione Reductase
7%
Glyceraldehyde-3-Phosphate Dehydrogenases
92%
Ions
14%
L-Lactate Dehydrogenase
5%
Light
4%
Metals
10%
Peptides
45%
Peroxides
89%
Proteins
26%
Rose Bengal
8%
Singlet Oxygen
100%
Sulfhydryl Compounds
31%
Kemiske forbindelser
Ascorbate
6%
Dioxygen
34%
Dye
3%
Enzyme Activity
9%
Enzyme Inhibition
7%
EPR Spectroscopy
5%
Glutathione
5%
Glyceraldehyde 3-Phosphate
93%
Lactate
5%
Metal Ion
11%
Peptide
40%
Peroxide
63%
Photooxidation
6%
Protein
29%
Reaction Stoichiometry
9%
Reaction Yield
2%
Rose Bengal
7%
Thiol
24%
Time
2%
Trolox
7%