Infectious hepatitis C viruses of genotype 3A and 4A and uses thereof: Patent #: 8,946,398

TY - PAT

T1 - Infectious hepatitis C viruses of genotype 3A and 4A and uses thereof

T2 - Patent #: 8,946,398

AU - Gottwein, Judith Margarete

AU - Scheel, Troels Kasper Hoyer

AU - Purcell, Robert E

AU - Bukh, Jens

PY - 2015/2/3

Y1 - 2015/2/3

N2 - The present invention relates to molecular approaches to the production of nucleic acid sequences, which comprises the genome of infectious hepatitis C virus. In particular, invention provides nucleic acid sequences which comprise the genomes of infectious hepatitis C viruses of either genotype 3a (strain S52) or genotype 4a (strain ED43). The invention therefore relates to the use of the nucleic acid sequences and polypeptides encoded by all or part of the sequences in the development of vaccines and diagnostic assays for HCV and in the development of screening assays for the identification of antiviral agents for HCV. The invention therefore also relates to the use of viral particles derived from laboratory animals infected with S52 and ED43 viruses.

AB - The present invention relates to molecular approaches to the production of nucleic acid sequences, which comprises the genome of infectious hepatitis C virus. In particular, invention provides nucleic acid sequences which comprise the genomes of infectious hepatitis C viruses of either genotype 3a (strain S52) or genotype 4a (strain ED43). The invention therefore relates to the use of the nucleic acid sequences and polypeptides encoded by all or part of the sequences in the development of vaccines and diagnostic assays for HCV and in the development of screening assays for the identification of antiviral agents for HCV. The invention therefore also relates to the use of viral particles derived from laboratory animals infected with S52 and ED43 viruses.

M3 - Patent

M1 - WO2011/038737

Y2 - 2012/07/26

ER -