Infectious endocarditis caused by Escherichia coli

Trine Kiilerich Lauridsen; Magnus Arpi; Thomas Fritz-Hansen; Niels Frimodt-Møller; Niels Eske Bruun

doi:10.3109/00365548.2011.554432

Infectious endocarditis caused by Escherichia coli

Trine Kiilerich Lauridsen, Magnus Arpi, Thomas Fritz-Hansen, Niels Frimodt-Møller, Niels Eske Bruun

Institut for Klinisk Medicin

10 Citationer (Scopus)

Abstract

Although Escherichia coli is among the most common causes of Gram-negative bacteraemia, infectious endocarditis (IE) due to this pathogen is rare. A 67-y-old male without a previous medical history presented with a new mitral regurgitation murmur and persisting E. coli bacteraemia in spite of broad-spectrum intravenous antibiotics. Transthoracic and transoesophageal echocardiography revealed a severe mitral endocarditis. E. coli DNA was identified from the mitral valve and the vegetation, and no other pathogen was found. The case was further complicated by spondylodiscitis and bilateral endophthalmitis. Extra-intestinal pathogenic E. coli (ExPEC) are able to colonize tissue outside the gastrointestinal tract and contain a variety of virulence factors that may enable the pathogens to invade and induce infections in the cardiac endothelia. In these cases echocardiography as the imaging technology is of paramount importance for the correct diagnosis and treatment.

Originalsprog	Engelsk
Tidsskrift	Scandinavian Journal of Infectious Diseases
Vol/bind	43
Udgave nummer	6-7
Sider (fra-til)	545-6
Antal sider	2
ISSN	0036-5548
DOI	https://doi.org/10.3109/00365548.2011.554432
Status	Udgivet - 1 jul. 2011

Adgang til dokumentet

10.3109/00365548.2011.554432

Citationsformater

@article{06fe5650def04cf8883a8017d3406e7e,

title = "Infectious endocarditis caused by Escherichia coli",

abstract = "Although Escherichia coli is among the most common causes of Gram-negative bacteraemia, infectious endocarditis (IE) due to this pathogen is rare. A 67-y-old male without a previous medical history presented with a new mitral regurgitation murmur and persisting E. coli bacteraemia in spite of broad-spectrum intravenous antibiotics. Transthoracic and transoesophageal echocardiography revealed a severe mitral endocarditis. E. coli DNA was identified from the mitral valve and the vegetation, and no other pathogen was found. The case was further complicated by spondylodiscitis and bilateral endophthalmitis. Extra-intestinal pathogenic E. coli (ExPEC) are able to colonize tissue outside the gastrointestinal tract and contain a variety of virulence factors that may enable the pathogens to invade and induce infections in the cardiac endothelia. In these cases echocardiography as the imaging technology is of paramount importance for the correct diagnosis and treatment.",

author = "Lauridsen, {Trine Kiilerich} and Magnus Arpi and Thomas Fritz-Hansen and Niels Frimodt-M{\o}ller and Bruun, {Niels Eske}",

year = "2011",

month = jul,

day = "1",

doi = "10.3109/00365548.2011.554432",

language = "English",

volume = "43",

pages = "545--6",

journal = "Scandinavian Journal of Infectious Diseases",

issn = "0036-5548",

publisher = "Taylor & Francis",

number = "6-7",

}

TY - JOUR

T1 - Infectious endocarditis caused by Escherichia coli

AU - Lauridsen, Trine Kiilerich

AU - Arpi, Magnus

AU - Fritz-Hansen, Thomas

AU - Frimodt-Møller, Niels

AU - Bruun, Niels Eske

PY - 2011/7/1

Y1 - 2011/7/1

N2 - Although Escherichia coli is among the most common causes of Gram-negative bacteraemia, infectious endocarditis (IE) due to this pathogen is rare. A 67-y-old male without a previous medical history presented with a new mitral regurgitation murmur and persisting E. coli bacteraemia in spite of broad-spectrum intravenous antibiotics. Transthoracic and transoesophageal echocardiography revealed a severe mitral endocarditis. E. coli DNA was identified from the mitral valve and the vegetation, and no other pathogen was found. The case was further complicated by spondylodiscitis and bilateral endophthalmitis. Extra-intestinal pathogenic E. coli (ExPEC) are able to colonize tissue outside the gastrointestinal tract and contain a variety of virulence factors that may enable the pathogens to invade and induce infections in the cardiac endothelia. In these cases echocardiography as the imaging technology is of paramount importance for the correct diagnosis and treatment.

AB - Although Escherichia coli is among the most common causes of Gram-negative bacteraemia, infectious endocarditis (IE) due to this pathogen is rare. A 67-y-old male without a previous medical history presented with a new mitral regurgitation murmur and persisting E. coli bacteraemia in spite of broad-spectrum intravenous antibiotics. Transthoracic and transoesophageal echocardiography revealed a severe mitral endocarditis. E. coli DNA was identified from the mitral valve and the vegetation, and no other pathogen was found. The case was further complicated by spondylodiscitis and bilateral endophthalmitis. Extra-intestinal pathogenic E. coli (ExPEC) are able to colonize tissue outside the gastrointestinal tract and contain a variety of virulence factors that may enable the pathogens to invade and induce infections in the cardiac endothelia. In these cases echocardiography as the imaging technology is of paramount importance for the correct diagnosis and treatment.

U2 - 10.3109/00365548.2011.554432

DO - 10.3109/00365548.2011.554432

M3 - Journal article

SN - 0036-5548

VL - 43

SP - 545

EP - 546

JO - Scandinavian Journal of Infectious Diseases

JF - Scandinavian Journal of Infectious Diseases

IS - 6-7

ER -

Infectious endocarditis caused by Escherichia coli

Abstract

Adgang til dokumentet

Fingeraftryk

Citationsformater