Impact of trial design on the estimation of drug potency and power in clinical trials of haemophilia with inhibitors

Malte Selch Larsen; Rasmus Vestergaard Juul; Mads Kreilgaard; Annemarie T. Kristensen; Ulrika S. H. Simonsson

doi:10.1016/j.ejps.2018.07.056

Impact of trial design on the estimation of drug potency and power in clinical trials of haemophilia with inhibitors

Malte Selch Larsen, Rasmus Vestergaard Juul, Mads Kreilgaard, Annemarie T. Kristensen, Ulrika S. H. Simonsson

2 Citationer (Scopus)

Originalsprog	Engelsk
Tidsskrift	European Journal of Pharmaceutical Sciences
Vol/bind	123
Sider (fra-til)	531-538
ISSN	0928-0987
DOI	https://doi.org/10.1016/j.ejps.2018.07.056
Status	Udgivet - 15 okt. 2018

Adgang til dokumentet

10.1016/j.ejps.2018.07.056

Citationsformater

@article{ac1c481724a54d319c76fe271b8c6b20,

title = "Impact of trial design on the estimation of drug potency and power in clinical trials of haemophilia with inhibitors",

keywords = "Haemophilia with inhibitors, Clinical trial design, Repeated time-to-event modelling, Drug potency, Statistical power",

author = "Larsen, {Malte Selch} and Juul, {Rasmus Vestergaard} and Mads Kreilgaard and Kristensen, {Annemarie T.} and Simonsson, {Ulrika S. H.}",

year = "2018",

month = oct,

day = "15",

doi = "10.1016/j.ejps.2018.07.056",

language = "English",

volume = "123",

pages = "531--538",

journal = "Norvegica Pharmaceutica Acta",

issn = "0928-0987",

publisher = "Elsevier",

}

TY - JOUR

T1 - Impact of trial design on the estimation of drug potency and power in clinical trials of haemophilia with inhibitors

AU - Larsen, Malte Selch

AU - Juul, Rasmus Vestergaard

AU - Kreilgaard, Mads

AU - Kristensen, Annemarie T.

AU - Simonsson, Ulrika S. H.

PY - 2018/10/15

Y1 - 2018/10/15

KW - Haemophilia with inhibitors

KW - Clinical trial design

KW - Repeated time-to-event modelling

KW - Drug potency

KW - Statistical power

U2 - 10.1016/j.ejps.2018.07.056

DO - 10.1016/j.ejps.2018.07.056

M3 - Journal article

C2 - 30077714

SN - 0928-0987

VL - 123

SP - 531

EP - 538

JO - Norvegica Pharmaceutica Acta

JF - Norvegica Pharmaceutica Acta

ER -

Impact of trial design on the estimation of drug potency and power in clinical trials of haemophilia with inhibitors

Adgang til dokumentet

Fingeraftryk

Citationsformater