Impact of postprandial glycaemia on health and prevention of disease

TY - JOUR

T1 - Impact of postprandial glycaemia on health and prevention of disease

AU - Blaak, E E

AU - Antoine, J-M

AU - Benton, D

AU - Björck, I

AU - Bozzetto, L

AU - Brouns, F

AU - Diamant, M

AU - Dye, L

AU - Hulshof, T

AU - Holst, J J

AU - Lamport, D J

AU - Laville, M

AU - Lawton, C L

AU - Meheust, A

AU - Nilson, A

AU - Normand, Signe

AU - Rivellese, A A

AU - Theis, S

AU - Torekov, Signe Sørensen

AU - Vinoy, S

N1 - © 2012 ILSI Europe. obesity reviews © 2012 International Association for the Study of Obesity.

PY - 2012/10

Y1 - 2012/10

N2 - Postprandial glucose, together with related hyperinsulinemia and lipidaemia, has been implicated in the development of chronic metabolic diseases like obesity, type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). In this review, available evidence is discussed on postprandial glucose in relation to body weight control, the development of oxidative stress, T2DM, and CVD and in maintaining optimal exercise and cognitive performance. There is mechanistic evidence linking postprandial glycaemia or glycaemic variability to the development of these conditions or in the impairment in cognitive and exercise performance. Nevertheless, postprandial glycaemia is interrelated with many other (risk) factors as well as to fasting glucose. In many studies, meal-related glycaemic response is not sufficiently characterized, or the methodology with respect to the description of food or meal composition, or the duration of the measurement of postprandial glycaemia is limited. It is evident that more randomized controlled dietary intervention trials using effective low vs. high glucose response diets are necessary in order to draw more definite conclusions on the role of postprandial glycaemia in relation to health and disease. Also of importance is the evaluation of the potential role of the time course of postprandial glycaemia.

AB - Postprandial glucose, together with related hyperinsulinemia and lipidaemia, has been implicated in the development of chronic metabolic diseases like obesity, type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). In this review, available evidence is discussed on postprandial glucose in relation to body weight control, the development of oxidative stress, T2DM, and CVD and in maintaining optimal exercise and cognitive performance. There is mechanistic evidence linking postprandial glycaemia or glycaemic variability to the development of these conditions or in the impairment in cognitive and exercise performance. Nevertheless, postprandial glycaemia is interrelated with many other (risk) factors as well as to fasting glucose. In many studies, meal-related glycaemic response is not sufficiently characterized, or the methodology with respect to the description of food or meal composition, or the duration of the measurement of postprandial glycaemia is limited. It is evident that more randomized controlled dietary intervention trials using effective low vs. high glucose response diets are necessary in order to draw more definite conclusions on the role of postprandial glycaemia in relation to health and disease. Also of importance is the evaluation of the potential role of the time course of postprandial glycaemia.

U2 - 10.1111/j.1467-789X.2012.01011.x

DO - 10.1111/j.1467-789X.2012.01011.x

M3 - Journal article

C2 - 22780564

SN - 1467-7881

VL - 13

SP - 923

EP - 984

JO - Obesity Reviews

JF - Obesity Reviews

IS - 10

ER -