Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation

Medicin og biovidenskab

• 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid 24%
• Amino Acids 6%
• Amino Acids, Peptides, and Proteins 16%
• Antioxidants 6%
• Bilirubin 8%
• chloramine 14%
• Chloramines 15%
• Digestion 7%
• Enzymes 4%
• Glutathione 15%
• Hydrogen Peroxide 8%
• Hypochlorous Acid 100%
• Lysine 67%
• Methionine 18%
• Monocytes 7%
• Neutrophils 6%
• Nitrogen 68%
• Oxidants 9%
• Peroxidase 8%
• Proteins 25%
• Spin Trapping 13%
• Uric Acid 8%

Kemiske forbindelser

• Acid 6%
• Amino Groups 8%
• Antioxidant Agent 7%
• Ascorbate 22%
• Bilirubin 11%
• Chloramine 28%
• Cleavage 6%
• Fragmentation 57%
• Glutathione 17%
• Homolysis 12%
• Hydrogen Peroxide 7%
• Hypochlorite 60%
• Lysine 9%
• Lysine Residue 77%
• Methionine 20%
• Peptide 5%
• Protein 28%
• Reaction Yield 4%
• Spin Trapping 11%
• Trolox 25%