Hybrid Imaging: PET-CT and PET-MRI

Barbara Malene Fischer, Johan Löfgren

Abstract

This chapter provides a brief introduction to the PET technology focusing on the evolution from stand-alone PET to PET-CT and the continuous improvement of the PET-CT technology during the last 10 years. The clinical significance of the development of hybrid PET-CT scanners is described together with illustrative examples of the importance of fused functional and anatomical imaging. Despite its widespread use and impact in many oncological settings, PET-CT has some limitations: i.e., radiation dose, limited soft tissue contrast, and the sequential acquiring of PET and CT data. In an attempt to solve these issues, the hybrid PET-MRI scanner was introduced, after approximately 20 years of research. The technical development of the PET-MRI scanner is briefly discussed in this chapter, together with an introduction to the three different PET-MRI systems currently available. The PET-MR technology was launched without any obvious “killer-indication,” apart from perhaps brain imaging. The published literature on clinical use of PET-MRI will be presented, and trends for the future development and perspectives on the use of both PET-CT and PET-MR in multifunctional oncology imaging will be discussed.

OriginalsprogEngelsk
TitelFunctional Imaging in Oncology : Biophysical Basis and Technical Approaches - Volume 1
RedaktørerAntonio Luna, Joan C. Vilanova, L. Celso Hygino Da Cruz Jr., Santiago E. Rossi
Antal sider20
Vol/bind1
ForlagSpringer Publishing Company
Publikationsdato1 jan. 2014
Sider411-430
ISBN (Trykt)978-3-642-40411-5
ISBN (Elektronisk)978-3-642-40412-2
DOI
StatusUdgivet - 1 jan. 2014

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