Hippo signalling directs intestinal fate

Marie Catherine M le Bouteiller; Kim Bak Jensen

Hippo signalling directs intestinal fate

Marie Catherine M le Bouteiller, Kim Bak Jensen

7 Citationer (Scopus)

Abstract

Hippo signalling has been associated with many important tissue functions including the regulation of organ size. In the intestinal epithelium differing functions have been proposed for the effectors of Hippo signalling, YAP and TAZ1. These are now shown to have a dual role in the intestinal epithelium, regulating both stem cell proliferation and differentiation along a specific secretory lineage.

Originalsprog	Engelsk
Tidsskrift	Nature Cell Biology
Vol/bind	17
Udgave nummer	1
Sider (fra-til)	5-6
Antal sider	2
ISSN	1465-7392
Status	Udgivet - 1 jan. 2015

Citationsformater

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AB - Hippo signalling has been associated with many important tissue functions including the regulation of organ size. In the intestinal epithelium differing functions have been proposed for the effectors of Hippo signalling, YAP and TAZ1. These are now shown to have a dual role in the intestinal epithelium, regulating both stem cell proliferation and differentiation along a specific secretory lineage.

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Hippo signalling directs intestinal fate

Abstract

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Citationsformater