High diversity of extended-spectrum ß-lactamases in Escherichia coli isolates from Italian broiler flocks

Valeria Bortolaia; Luca Guardabassi; Marcello Trevisani; Magne Bisgaard; Luciano Venturi; Anders Miki Bojesen

doi:10.1128/AAC.01361-09

High diversity of extended-spectrum ß-lactamases in Escherichia coli isolates from Italian broiler flocks

Valeria Bortolaia, Luca Guardabassi, Marcello Trevisani, Magne Bisgaard, Luciano Venturi, Anders Miki Bojesen

61 Citationer (Scopus)

Abstract

We characterized 67 Escherichia coli isolates with reduced susceptibility to cefotaxime or ceftiofur obtained from healthy broilers housed in five Italian farms. The bla_CTX-M-1, bla_CTX-M-32 and bla _SHV-12. β-lactamase genes were identified on IncI1, IncN, or IncFIB plasmids. Considerable genetic diversity was detected among the extended-spectru. β-lactamase (ESBL)-producing isolates, and we identified indistinguishable strains in unrelated farms and indistinguishable plasmids in genetically unrelated strains. The detection of highly mobile plasmids suggests a potential animal reservoir fo. β-lactamase genes.

Originalsprog	Engelsk
Tidsskrift	Antimicrobial Agents and Chemotherapy
Vol/bind	54
Udgave nummer	4
Sider (fra-til)	1623-1626
Antal sider	4
ISSN	0066-4804
DOI	https://doi.org/10.1128/AAC.01361-09
Status	Udgivet - apr. 2010

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T1 - High diversity of extended-spectrum ß-lactamases in Escherichia coli isolates from Italian broiler flocks

AU - Bortolaia, Valeria

AU - Guardabassi, Luca

AU - Trevisani, Marcello

AU - Bisgaard, Magne

AU - Venturi, Luciano

AU - Bojesen, Anders Miki

PY - 2010/4

Y1 - 2010/4

N2 - We characterized 67 Escherichia coli isolates with reduced susceptibility to cefotaxime or ceftiofur obtained from healthy broilers housed in five Italian farms. The blaCTX-M-1, blaCTX-M-32 and bla SHV-12. β-lactamase genes were identified on IncI1, IncN, or IncFIB plasmids. Considerable genetic diversity was detected among the extended-spectru. β-lactamase (ESBL)-producing isolates, and we identified indistinguishable strains in unrelated farms and indistinguishable plasmids in genetically unrelated strains. The detection of highly mobile plasmids suggests a potential animal reservoir fo. β-lactamase genes.

AB - We characterized 67 Escherichia coli isolates with reduced susceptibility to cefotaxime or ceftiofur obtained from healthy broilers housed in five Italian farms. The blaCTX-M-1, blaCTX-M-32 and bla SHV-12. β-lactamase genes were identified on IncI1, IncN, or IncFIB plasmids. Considerable genetic diversity was detected among the extended-spectru. β-lactamase (ESBL)-producing isolates, and we identified indistinguishable strains in unrelated farms and indistinguishable plasmids in genetically unrelated strains. The detection of highly mobile plasmids suggests a potential animal reservoir fo. β-lactamase genes.

KW - Former LIFE faculty

U2 - 10.1128/AAC.01361-09

DO - 10.1128/AAC.01361-09

M3 - Journal article

C2 - 20100875

SN - 0066-4804

VL - 54

SP - 1623

EP - 1626

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 4

ER -

High diversity of extended-spectrum ß-lactamases in Escherichia coli isolates from Italian broiler flocks

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