Hemoglobin levels and blood pressure are associated in rural black Africans

Jon Bjarke Jarløv Rasmussen; David L Mwaniki; Lydia U Kaduka; Mike K Boit; Knut Borch-Johnsen; Henrik Friis; Dirk Lund Christensen

doi:10.1002/ajhb.22758

Hemoglobin levels and blood pressure are associated in rural black Africans

Jon Bjarke Jarløv Rasmussen, David L Mwaniki, Lydia U Kaduka, Mike K Boit, Knut Borch-Johnsen, Henrik Friis, Dirk Lund Christensen

9 Citationer (Scopus)

Abstract

Objectives: The association between blood levels of hemoglobin (B-hgb) and blood pressure (BP) has been widely investigated in Caucasians and Asians but there is a paucity of data in rural black Africans. The objective was to investigate the association between B-hgb and BP in a rural black African population. Methods: A cross-sectional study was conducted in three districts in Kenya (Bondo, Kitui, and Transmara) with the inclusion of participants aged ≥17 years. Background information, anthropometry, BP, B-hgb, hepatic insulin resistance (HOMA2-IR), standard lipid profile, and oral glucose tolerance test were obtained in each participant. Results: Background characteristics among 1,167 participants showed that anemic and non-anemic participants differed significantly from each other as there were more women, lower body mass index and waist circumference (WC), lower degree of hepatic insulin resistance and plasma cholesterols among the anemic participants. Furthermore, anemic participants had significantly lower systolic and diastolic BP (P<0.01) but not a significantly different prevalence of hypertension (P=0.08). Multivariate linear regression models adjusted for-age, sex, plasma total-cholesterol, WC, Log2(HOMA2-IR), ethnicity, and smoking status-revealed that B-hgb (per mmol/l increment) was significantly associated with systolic BP (estimate: 1.18 (0.37-1.98)) and diastolic BP (estimate: 1.06 (0.54-1.57)) (P<0.01). Conclusions: B-hgb is associated with BP in rural black Africans.

Originalsprog	Engelsk
Tidsskrift	American Journal of Human Biology
Vol/bind	28
Udgave nummer	1
Sider (fra-til)	145-148
Antal sider	4
ISSN	1042-0533
DOI	https://doi.org/10.1002/ajhb.22758
Status	Udgivet - 1 jan. 2016

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10.1002/ajhb.22758

Citationsformater

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title = "Hemoglobin levels and blood pressure are associated in rural black Africans",

abstract = "Objectives: The association between blood levels of hemoglobin (B-hgb) and blood pressure (BP) has been widely investigated in Caucasians and Asians but there is a paucity of data in rural black Africans. The objective was to investigate the association between B-hgb and BP in a rural black African population. Methods: A cross-sectional study was conducted in three districts in Kenya (Bondo, Kitui, and Transmara) with the inclusion of participants aged ≥17 years. Background information, anthropometry, BP, B-hgb, hepatic insulin resistance (HOMA2-IR), standard lipid profile, and oral glucose tolerance test were obtained in each participant. Results: Background characteristics among 1,167 participants showed that anemic and non-anemic participants differed significantly from each other as there were more women, lower body mass index and waist circumference (WC), lower degree of hepatic insulin resistance and plasma cholesterols among the anemic participants. Furthermore, anemic participants had significantly lower systolic and diastolic BP (P<0.01) but not a significantly different prevalence of hypertension (P=0.08). Multivariate linear regression models adjusted for-age, sex, plasma total-cholesterol, WC, Log2(HOMA2-IR), ethnicity, and smoking status-revealed that B-hgb (per mmol/l increment) was significantly associated with systolic BP (estimate: 1.18 (0.37-1.98)) and diastolic BP (estimate: 1.06 (0.54-1.57)) (P<0.01). Conclusions: B-hgb is associated with BP in rural black Africans.",

author = "Rasmussen, {Jon Bjarke Jarl{\o}v} and Mwaniki, {David L} and Kaduka, {Lydia U} and Boit, {Mike K} and Knut Borch-Johnsen and Henrik Friis and Christensen, {Dirk Lund}",

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T1 - Hemoglobin levels and blood pressure are associated in rural black Africans

AU - Rasmussen, Jon Bjarke Jarløv

AU - Mwaniki, David L

AU - Kaduka, Lydia U

AU - Boit, Mike K

AU - Borch-Johnsen, Knut

AU - Friis, Henrik

AU - Christensen, Dirk Lund

N1 - CURIS 2016 NEXS 011

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Objectives: The association between blood levels of hemoglobin (B-hgb) and blood pressure (BP) has been widely investigated in Caucasians and Asians but there is a paucity of data in rural black Africans. The objective was to investigate the association between B-hgb and BP in a rural black African population. Methods: A cross-sectional study was conducted in three districts in Kenya (Bondo, Kitui, and Transmara) with the inclusion of participants aged ≥17 years. Background information, anthropometry, BP, B-hgb, hepatic insulin resistance (HOMA2-IR), standard lipid profile, and oral glucose tolerance test were obtained in each participant. Results: Background characteristics among 1,167 participants showed that anemic and non-anemic participants differed significantly from each other as there were more women, lower body mass index and waist circumference (WC), lower degree of hepatic insulin resistance and plasma cholesterols among the anemic participants. Furthermore, anemic participants had significantly lower systolic and diastolic BP (P<0.01) but not a significantly different prevalence of hypertension (P=0.08). Multivariate linear regression models adjusted for-age, sex, plasma total-cholesterol, WC, Log2(HOMA2-IR), ethnicity, and smoking status-revealed that B-hgb (per mmol/l increment) was significantly associated with systolic BP (estimate: 1.18 (0.37-1.98)) and diastolic BP (estimate: 1.06 (0.54-1.57)) (P<0.01). Conclusions: B-hgb is associated with BP in rural black Africans.

AB - Objectives: The association between blood levels of hemoglobin (B-hgb) and blood pressure (BP) has been widely investigated in Caucasians and Asians but there is a paucity of data in rural black Africans. The objective was to investigate the association between B-hgb and BP in a rural black African population. Methods: A cross-sectional study was conducted in three districts in Kenya (Bondo, Kitui, and Transmara) with the inclusion of participants aged ≥17 years. Background information, anthropometry, BP, B-hgb, hepatic insulin resistance (HOMA2-IR), standard lipid profile, and oral glucose tolerance test were obtained in each participant. Results: Background characteristics among 1,167 participants showed that anemic and non-anemic participants differed significantly from each other as there were more women, lower body mass index and waist circumference (WC), lower degree of hepatic insulin resistance and plasma cholesterols among the anemic participants. Furthermore, anemic participants had significantly lower systolic and diastolic BP (P<0.01) but not a significantly different prevalence of hypertension (P=0.08). Multivariate linear regression models adjusted for-age, sex, plasma total-cholesterol, WC, Log2(HOMA2-IR), ethnicity, and smoking status-revealed that B-hgb (per mmol/l increment) was significantly associated with systolic BP (estimate: 1.18 (0.37-1.98)) and diastolic BP (estimate: 1.06 (0.54-1.57)) (P<0.01). Conclusions: B-hgb is associated with BP in rural black Africans.

U2 - 10.1002/ajhb.22758

DO - 10.1002/ajhb.22758

M3 - Journal article

C2 - 26087952

SN - 1042-0533

VL - 28

SP - 145

EP - 148

JO - American Journal of Human Biology

JF - American Journal of Human Biology

IS - 1

ER -

Hemoglobin levels and blood pressure are associated in rural black Africans

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