Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

Robin N. Beaumont; Nicole M. Warrington; Alana Cavadino; Jessica Tyrrell; Michael Nodzenski; Momoko Horikoshi; Frank Geller; Ronny Myhre; Rebecca C. Richmond; Lavinia Paternoster; Jonathan P. Bradfield; Eskil Kreiner-Moller; Ville Huikari; Sarah Metrustry; Kathryn L. Lunetta; Jodie N. Painter; Jouke-Jan Hottenga; Catherine Allard; Sheila J. Barton; Ana Espinosa; Julie A. Marsh; Catherine Potter; Ge Zhang; Wei Ang; Diane J. Berry; Luigi Bouchard; Shikta Das; Hakon Hakonarson; Jani Heikkinen; Oyvind Helgeland; Berthold Hocher; Albert Hofman; Hazel M. Inskip; Samuel E. Jones; Manolis Kogevinas; Penelope A. Lind; Letizia Marullo; Sarah E. Medland; Anna Murray; Jeffrey C. Murray; Pal R. Njolstad; Ellen A. Nohr; Christoph Reichetzeder; Susan M. Ring; Katherine S. Ruth; Loreto Santa-Marina; Denise M. Scholtens; Sylvain Sebert; Verena Sengpiel; Marcus A. Tuke; Marc Vaudel; Michael N. Weedon; Gonneke Willemsen; Andrew R. Wood; Hanieh Yaghootkar; Louis J. Muglia; Meike Bartels; Caroline L. Relton; Craig E. Pennell; Leda Chatzi; Xavier Estivill; John W. Holloway; Dorret I. Boomsma; Grant W. Montgomery; Joanne M. Murabito; Tim D. Spector; Christine Power; Marjo-Ritta Jarvelin; Hans Bisgaard; Struan F. A. Grant; Thorkild I. A. Sørensen; Vincent W. Jaddoe; Bo Jacobsson; Mads Melbye; Mark I. McCarthy; Andrew T. Hattersley; M. Geoffrey Hayes; Timothy M. Frayling; Marie-France Hivert; Janine F. Felix; Elina Hypponen; William L., Jr. Lowe; David M. Evans; Debbie A. Lawlor; Bjarke Feenstra; Rachel M. Freathy

doi:10.1093/hmg/ddx429

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

Robin N. Beaumont, Nicole M. Warrington, Alana Cavadino, Jessica Tyrrell, Michael Nodzenski, Momoko Horikoshi, Frank Geller, Ronny Myhre, Rebecca C. Richmond, Lavinia Paternoster, Jonathan P. Bradfield, Eskil Kreiner-Moller, Ville Huikari, Sarah Metrustry, Kathryn L. Lunetta, Jodie N. Painter, Jouke-Jan Hottenga, Catherine Allard, Sheila J. Barton, Ana EspinosaJulie A. Marsh, Catherine Potter, Ge Zhang, Wei Ang, Diane J. Berry, Luigi Bouchard, Shikta Das, Hakon Hakonarson, Jani Heikkinen, Oyvind Helgeland, Berthold Hocher, Albert Hofman, Hazel M. Inskip, Samuel E. Jones, Manolis Kogevinas, Penelope A. Lind, Letizia Marullo, Sarah E. Medland, Anna Murray, Jeffrey C. Murray, Pal R. Njolstad, Ellen A. Nohr, Christoph Reichetzeder, Susan M. Ring, Katherine S. Ruth, Loreto Santa-Marina, Denise M. Scholtens, Sylvain Sebert, Verena Sengpiel, Marcus A. Tuke, Marc Vaudel, Michael N. Weedon, Gonneke Willemsen, Andrew R. Wood, Hanieh Yaghootkar, Louis J. Muglia, Meike Bartels, Caroline L. Relton, Craig E. Pennell, Leda Chatzi, Xavier Estivill, John W. Holloway, Dorret I. Boomsma, Grant W. Montgomery, Joanne M. Murabito, Tim D. Spector, Christine Power, Marjo-Ritta Jarvelin, Hans Bisgaard, Struan F. A. Grant, Thorkild I. A. Sørensen, Vincent W. Jaddoe, Bo Jacobsson, Mads Melbye, Mark I. McCarthy, Andrew T. Hattersley, M. Geoffrey Hayes, Timothy M. Frayling, Marie-France Hivert, Janine F. Felix, Elina Hypponen, William L., Jr. Lowe, David M. Evans, Debbie A. Lawlor, Bjarke Feenstra, Rachel M. Freathy

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Originalsprog	Engelsk
Tidsskrift	Human Molecular Genetics
Vol/bind	27
Udgave nummer	4
Sider (fra-til)	742-756
Antal sider	15
ISSN	0964-6906
DOI	https://doi.org/10.1093/hmg/ddx429
Status	Udgivet - 2018

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10.1093/hmg/ddx429Licens: CC BY

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal geneticsForlagets udgivne version, 452 KBLicens: CC BY

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Beaumont, R. N., Warrington, N. M., Cavadino, A., Tyrrell, J., Nodzenski, M., Horikoshi, M., Geller, F., Myhre, R., Richmond, R. C., Paternoster, L., Bradfield, J. P., Kreiner-Moller, E., Huikari, V., Metrustry, S., Lunetta, K. L., Painter, J. N., Hottenga, J-J., Allard, C., Barton, S. J., ... Freathy, R. M. (2018). Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. Human Molecular Genetics, 27(4), 742-756. https://doi.org/10.1093/hmg/ddx429

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. / Beaumont, Robin N.; Warrington, Nicole M.; Cavadino, Alana et al.

I: Human Molecular Genetics, Bind 27, Nr. 4, 2018, s. 742-756.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

Beaumont, RN, Warrington, NM, Cavadino, A, Tyrrell, J, Nodzenski, M, Horikoshi, M, Geller, F, Myhre, R, Richmond, RC, Paternoster, L, Bradfield, JP, Kreiner-Moller, E, Huikari, V, Metrustry, S, Lunetta, KL, Painter, JN, Hottenga, J-J, Allard, C, Barton, SJ, Espinosa, A, Marsh, JA, Potter, C, Zhang, G, Ang, W, Berry, DJ, Bouchard, L, Das, S, Hakonarson, H, Heikkinen, J, Helgeland, O, Hocher, B, Hofman, A, Inskip, HM, Jones, SE, Kogevinas, M, Lind, PA, Marullo, L, Medland, SE, Murray, A, Murray, JC, Njolstad, PR, Nohr, EA, Reichetzeder, C, Ring, SM, Ruth, KS, Santa-Marina, L, Scholtens, DM, Sebert, S, Sengpiel, V, Tuke, MA, Vaudel, M, Weedon, MN, Willemsen, G, Wood, AR, Yaghootkar, H, Muglia, LJ, Bartels, M, Relton, CL, Pennell, CE, Chatzi, L, Estivill, X, Holloway, JW, Boomsma, DI, Montgomery, GW, Murabito, JM, Spector, TD, Power, C, Jarvelin, M-R, Bisgaard, H, Grant, SFA, Sørensen, TIA, Jaddoe, VW, Jacobsson, B, Melbye, M, McCarthy, MI, Hattersley, AT, Hayes, MG, Frayling, TM, Hivert, M-F, Felix, JF, Hypponen, E, Lowe, WLJ, Evans, DM, Lawlor, DA, Feenstra, B & Freathy, RM 2018, 'Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics', Human Molecular Genetics, bind 27, nr. 4, s. 742-756. https://doi.org/10.1093/hmg/ddx429

@article{fccc107f82514236bd938e20b01adffc,

title = "Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics",

author = "Beaumont, {Robin N.} and Warrington, {Nicole M.} and Alana Cavadino and Jessica Tyrrell and Michael Nodzenski and Momoko Horikoshi and Frank Geller and Ronny Myhre and Richmond, {Rebecca C.} and Lavinia Paternoster and Bradfield, {Jonathan P.} and Eskil Kreiner-Moller and Ville Huikari and Sarah Metrustry and Lunetta, {Kathryn L.} and Painter, {Jodie N.} and Jouke-Jan Hottenga and Catherine Allard and Barton, {Sheila J.} and Ana Espinosa and Marsh, {Julie A.} and Catherine Potter and Ge Zhang and Wei Ang and Berry, {Diane J.} and Luigi Bouchard and Shikta Das and Hakon Hakonarson and Jani Heikkinen and Oyvind Helgeland and Berthold Hocher and Albert Hofman and Inskip, {Hazel M.} and Jones, {Samuel E.} and Manolis Kogevinas and Lind, {Penelope A.} and Letizia Marullo and Medland, {Sarah E.} and Anna Murray and Murray, {Jeffrey C.} and Njolstad, {Pal R.} and Nohr, {Ellen A.} and Christoph Reichetzeder and Ring, {Susan M.} and Ruth, {Katherine S.} and Loreto Santa-Marina and Scholtens, {Denise M.} and Sylvain Sebert and Verena Sengpiel and Tuke, {Marcus A.} and Marc Vaudel and Weedon, {Michael N.} and Gonneke Willemsen and Wood, {Andrew R.} and Hanieh Yaghootkar and Muglia, {Louis J.} and Meike Bartels and Relton, {Caroline L.} and Pennell, {Craig E.} and Leda Chatzi and Xavier Estivill and Holloway, {John W.} and Boomsma, {Dorret I.} and Montgomery, {Grant W.} and Murabito, {Joanne M.} and Spector, {Tim D.} and Christine Power and Marjo-Ritta Jarvelin and Hans Bisgaard and Grant, {Struan F. A.} and S{\o}rensen, {Thorkild I. A.} and Jaddoe, {Vincent W.} and Bo Jacobsson and Mads Melbye and McCarthy, {Mark I.} and Hattersley, {Andrew T.} and Hayes, {M. Geoffrey} and Frayling, {Timothy M.} and Marie-France Hivert and Felix, {Janine F.} and Elina Hypponen and Lowe, {William L., Jr.} and Evans, {David M.} and Lawlor, {Debbie A.} and Bjarke Feenstra and Freathy, {Rachel M.}",

year = "2018",

doi = "10.1093/hmg/ddx429",

language = "English",

volume = "27",

pages = "742--756",

journal = "Human Molecular Genetics",

issn = "0964-6906",

publisher = "Oxford University Press",

number = "4",

}

TY - JOUR

T1 - Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

AU - Beaumont, Robin N.

AU - Warrington, Nicole M.

AU - Cavadino, Alana

AU - Tyrrell, Jessica

AU - Nodzenski, Michael

AU - Horikoshi, Momoko

AU - Geller, Frank

AU - Myhre, Ronny

AU - Richmond, Rebecca C.

AU - Paternoster, Lavinia

AU - Bradfield, Jonathan P.

AU - Kreiner-Moller, Eskil

AU - Huikari, Ville

AU - Metrustry, Sarah

AU - Lunetta, Kathryn L.

AU - Painter, Jodie N.

AU - Hottenga, Jouke-Jan

AU - Allard, Catherine

AU - Barton, Sheila J.

AU - Espinosa, Ana

AU - Marsh, Julie A.

AU - Potter, Catherine

AU - Zhang, Ge

AU - Ang, Wei

AU - Berry, Diane J.

AU - Bouchard, Luigi

AU - Das, Shikta

AU - Hakonarson, Hakon

AU - Heikkinen, Jani

AU - Helgeland, Oyvind

AU - Hocher, Berthold

AU - Hofman, Albert

AU - Inskip, Hazel M.

AU - Jones, Samuel E.

AU - Kogevinas, Manolis

AU - Lind, Penelope A.

AU - Marullo, Letizia

AU - Medland, Sarah E.

AU - Murray, Anna

AU - Murray, Jeffrey C.

AU - Njolstad, Pal R.

AU - Nohr, Ellen A.

AU - Reichetzeder, Christoph

AU - Ring, Susan M.

AU - Ruth, Katherine S.

AU - Santa-Marina, Loreto

AU - Scholtens, Denise M.

AU - Sebert, Sylvain

AU - Sengpiel, Verena

AU - Tuke, Marcus A.

AU - Vaudel, Marc

AU - Weedon, Michael N.

AU - Willemsen, Gonneke

AU - Wood, Andrew R.

AU - Yaghootkar, Hanieh

AU - Muglia, Louis J.

AU - Bartels, Meike

AU - Relton, Caroline L.

AU - Pennell, Craig E.

AU - Chatzi, Leda

AU - Estivill, Xavier

AU - Holloway, John W.

AU - Boomsma, Dorret I.

AU - Montgomery, Grant W.

AU - Murabito, Joanne M.

AU - Spector, Tim D.

AU - Power, Christine

AU - Jarvelin, Marjo-Ritta

AU - Bisgaard, Hans

AU - Grant, Struan F. A.

AU - Sørensen, Thorkild I. A.

AU - Jaddoe, Vincent W.

AU - Jacobsson, Bo

AU - Melbye, Mads

AU - McCarthy, Mark I.

AU - Hattersley, Andrew T.

AU - Hayes, M. Geoffrey

AU - Frayling, Timothy M.

AU - Hivert, Marie-France

AU - Felix, Janine F.

AU - Hypponen, Elina

AU - Lowe, William L., Jr.

AU - Evans, David M.

AU - Lawlor, Debbie A.

AU - Feenstra, Bjarke

AU - Freathy, Rachel M.

PY - 2018

Y1 - 2018

U2 - 10.1093/hmg/ddx429

DO - 10.1093/hmg/ddx429

M3 - Journal article

C2 - 29309628

SN - 0964-6906

VL - 27

SP - 742

EP - 756

JO - Human Molecular Genetics

JF - Human Molecular Genetics

IS - 4

ER -

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

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