Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

Symen Ligthart; Ahmad Vaez; Urmo Vosa; Maria G. Stathopoulou; Paul S. de Vries; Bram P. Prins; Peter J. Van der Most; Toshiko Tanaka; Elnaz Naderi; Lynda M. Rose; Ying Wu; Robert Karlsson; Maja Barbalic; Honghuang Lin; Rene Pool; Gu Zhu; Aurelien Mace; Carlo Sidore; Stella Trompet; Massimo Mangino; Maria Sabater-Lleal; John P. Kemp; Ali Abbasi; Tim Kacprowski; Niek Verweij; Albert V. Smith; Tao Huang; Carola Marzi; Mary F. Feitosa; Kurt K. Lohman; Marcus E. Kleber; Yuri Milaneschi; Christian Mueller; Mahmudul Huq; Efthymia Vlachopoulou; Leo-Pekka Lyytikainen; Christopher Oldmeadow; Joris Deelen; Markus Perola; Jing Zhao; Bjarke Feenstra; Marzyeh Amini; Jari Lahti; Katharina E. Schraut; Myriam Fornage; Bhoom Suktitipat; Wei-Min Chen; Xiaohui Li; Teresa Nutile; Giovanni Malerba; Jian'an Luan; Tom Bak; Nicholas Schork; Fabiola M. Del Greco; Elisabeth Thiering; Anubha Mahajan; Riccardo E. Marioni; Evelin Mihailov; Joel Eriksson; Ayse Bilge Ozel; Weihua Zhang; Maria Nethander; Yu-Ching Cheng; Stella Aslibekyan; Wei Ang; Ilaria Gandin; Loic Yengo; Laura Portas; Charles Kooperberg; Edith Hofer; Kumar B. Rajan; Claudia Schurmann; Wouter den Hollander; Tarunveer S. Ahluwalia; Jing Zhao; Harmen H. M. Draisma; Ian Ford; Nicholas Timpson; Alexander Teumer; Hongyan Huang; Simone Wahl; YongMei Liu; Jie Huang; Hae-Won Uh; Frank Geller; Peter K. Joshi; Lisa R. Yanek; Elisabetta Trabetti; Benjamin Lehne; Diego Vozzi; Marie Verbanck; Ginevra Biino; Yasaman Saba; Ingrid Meulenbelt; Jeff R. O'Connell; Markku Laakso; Franco Giulianini; Patrik K. E. Magnusson; Christie M. Ballantyne; Jouke Jan Hottenga; GrantW. Montgomery; Fernando Rivadineira; Rico Rueedi; Maristella Steri; Karl-Heinz Herzig; David J. Stott; Cristina Menni; Mattias Franberg; Beate St Pourcain; Stephan B. Felix; Tune H. Pers; Stephan J. L. Bakker; Peter Kraft; Annette Peters; Dhananjay Vaidya; Graciela Delgado; Johannes H. Smit; Vera Grossmann; Juha Sinisalo; Ilkka Seppala; Stephen R. Williams; Elizabeth G. Holliday; Matthijs Moed; Claudia Langenberg; Katri Raikkonen; Jingzhong Ding; Harry Campbell; Michele M. Sale; Yii-Der I. Chen; Alan L. James; Daniela Ruggiero; Nicole Soranzo; Catharina A. Hartman; Erin N. Smith; Gerald S. Berenson; Christian Fuchsberger; Dena Hernandez; Carla M. T. Tiesler; Vilmantas Giedraitis; David Liewald; Krista Fischer; Dan Mellstrom; Anders Larsson; Yunmei Wang; William R. Scott; Matthias Lorentzon; John Beilby; Kathleen A. Ryan; Craig E. Pennell; Dragana Vuckovic; Beverly Balkau; Maria Pina Concas; Reinhold Schmidt; Carlos F. Mendes de Leon; Erwin P. Bottinger; Margreet Kloppenburg; Lavinia Paternoster; Michael Boehnke; A. W. Musk; Gonneke Willemsen; David M. Evans; Pamela A. F. Madden; Mika Kahonen; Zoltan Kutalik; Magdalena Zoledziewska; Ville Karhunen; Stephen B. Kritchevsky; Naveed Sattar; Genevieve Lachance; Robert Clarke; Tamara B. Harris; Olli T. Raitakari; John R. Attia; Diana Van Heemst; Eero Kajantie; Rossella Sorice; Giovanni Gambaro; Robert A. Scott; Andrew A. Hicks; Luigi Ferrucci; Marie Standl; Cecilia M. Lindgren; John M. Starr; Magnus Karlsson; Lars Lind; Jun Z. Li; John C. Chambers; Trevor A. Mori; Eco J. C. N. de Geus; Andrew C. Heath; Nicholas G. Martin; Juha Auvinen; Brendan M. Buckley; Anton J. M. de Craen; Melanie Waldenberger; Konstantin Strauch; Thomas Meitinger; Rodney J. Scott; Mark McEvoy; Marian Beekman; Cristina Bombieri; Paul M. Ridker; Karen L. Mohlke; Nancy L. Pedersen; Alanna C. Morrison; Dorret I. Boomsma; John B. Whitfield; David P. Strachan; Albert Hofman; Peter Vollenweider; Francesco Cucca; Marjo-Riitta Jarvelin; J. Wouter Jukema; Tim D. Spector; Anders Hamsten; Tanja Zeller; Andre G. Uitterlinden; Matthias Nauck; Vilmundur Gudnason; Lu Qi; Harald Grallert; Ingrid B. Borecki; Jerome I. Rotter; Winfried Maerz; Philipp S. Wild; Marja-Liisa Lokki; Michael Boyle; Veikko Salomaa; Mads Melbye; Johan G. Eriksson; James F. Wilson; Brenda W. J. H. Penninx; Diane M. Becker; Bradford B. Worrall; Greg Gibson; Ronald M. Krauss; Marina Ciullo; Gianluigi Zaza; Nicholas J. Wareham; Albertine J. Oldehinkel; Lyle J. Palmer; Sarah S. Murray; Peter P. Pramstaller; Stefania Bandinelli; Joachim Heinrich; Erik Ingelsson; Ian J. Deary; Reedik Magi; Liesbeth Vandenput; Pim van der Harst; Karl C. Desch; Jaspal S. Kooner; Claes Ohlsson; Caroline Hayward; Terho Lehtimaki; Alan R. Shuldiner; Donna K. Arnett; Lawrence J. Beilin; Antonietta Robino; Philippe Froguel; Mario Pirastu; Tine Jess; Wolfgang Koenig; Ruth J. F. Loos; Denis A. Evans; Helena Schmidt; George Davey Smith; P. Eline Slagboom; Gudny Eiriksdottir; Andrew P. Morris; Bruce M. Psaty; Russell P. Tracy; Ilja M. Nolte; Eric Boerwinkle; Sophie Visvikis-Siest; Alex P. Reiner; Myron Gross; Joshua C. Bis; Lude Franke; Oscar H. Franco; Emelia J. Benjamin; Daniel I. Chasman; Josee Dupuis; Harold Snieder; Abbas Dehghan; Behrooz Z. Alizadeh

doi:10.1016/j.ajhg.2018.09.009

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

Symen Ligthart, Ahmad Vaez, Urmo Vosa, Maria G. Stathopoulou, Paul S. de Vries, Bram P. Prins, Peter J. Van der Most, Toshiko Tanaka, Elnaz Naderi, Lynda M. Rose, Ying Wu, Robert Karlsson, Maja Barbalic, Honghuang Lin, Rene Pool, Gu Zhu, Aurelien Mace, Carlo Sidore, Stella Trompet, Massimo ManginoMaria Sabater-Lleal, John P. Kemp, Ali Abbasi, Tim Kacprowski, Niek Verweij, Albert V. Smith, Tao Huang, Carola Marzi, Mary F. Feitosa, Kurt K. Lohman, Marcus E. Kleber, Yuri Milaneschi, Christian Mueller, Mahmudul Huq, Efthymia Vlachopoulou, Leo-Pekka Lyytikainen, Christopher Oldmeadow, Joris Deelen, Markus Perola, Jing Zhao, Bjarke Feenstra, Marzyeh Amini, Jari Lahti, Katharina E. Schraut, Myriam Fornage, Bhoom Suktitipat, Wei-Min Chen, Xiaohui Li, Teresa Nutile, Giovanni Malerba, Jian'an Luan, Tom Bak, Nicholas Schork, Fabiola M. Del Greco, Elisabeth Thiering, Anubha Mahajan, Riccardo E. Marioni, Evelin Mihailov, Joel Eriksson, Ayse Bilge Ozel, Weihua Zhang, Maria Nethander, Yu-Ching Cheng, Stella Aslibekyan, Wei Ang, Ilaria Gandin, Loic Yengo, Laura Portas, Charles Kooperberg, Edith Hofer, Kumar B. Rajan, Claudia Schurmann, Wouter den Hollander, Tarunveer S. Ahluwalia, Jing Zhao, Harmen H. M. Draisma, Ian Ford, Nicholas Timpson, Alexander Teumer, Hongyan Huang, Simone Wahl, YongMei Liu, Jie Huang, Hae-Won Uh, Frank Geller, Peter K. Joshi, Lisa R. Yanek, Elisabetta Trabetti, Benjamin Lehne, Diego Vozzi, Marie Verbanck, Ginevra Biino, Yasaman Saba, Ingrid Meulenbelt, Jeff R. O'Connell, Markku Laakso, Franco Giulianini, Patrik K. E. Magnusson, Christie M. Ballantyne, Jouke Jan Hottenga, GrantW. Montgomery, Fernando Rivadineira, Rico Rueedi, Maristella Steri, Karl-Heinz Herzig, David J. Stott, Cristina Menni, Mattias Franberg, Beate St Pourcain, Stephan B. Felix, Tune H. Pers, Stephan J. L. Bakker, Peter Kraft, Annette Peters, Dhananjay Vaidya, Graciela Delgado, Johannes H. Smit, Vera Grossmann, Juha Sinisalo, Ilkka Seppala, Stephen R. Williams, Elizabeth G. Holliday, Matthijs Moed, Claudia Langenberg, Katri Raikkonen, Jingzhong Ding, Harry Campbell, Michele M. Sale, Yii-Der I. Chen, Alan L. James, Daniela Ruggiero, Nicole Soranzo, Catharina A. Hartman, Erin N. Smith, Gerald S. Berenson, Christian Fuchsberger, Dena Hernandez, Carla M. T. Tiesler, Vilmantas Giedraitis, David Liewald, Krista Fischer, Dan Mellstrom, Anders Larsson, Yunmei Wang, William R. Scott, Matthias Lorentzon, John Beilby, Kathleen A. Ryan, Craig E. Pennell, Dragana Vuckovic, Beverly Balkau, Maria Pina Concas, Reinhold Schmidt, Carlos F. Mendes de Leon, Erwin P. Bottinger, Margreet Kloppenburg, Lavinia Paternoster, Michael Boehnke, A. W. Musk, Gonneke Willemsen, David M. Evans, Pamela A. F. Madden, Mika Kahonen, Zoltan Kutalik, Magdalena Zoledziewska, Ville Karhunen, Stephen B. Kritchevsky, Naveed Sattar, Genevieve Lachance, Robert Clarke, Tamara B. Harris, Olli T. Raitakari, John R. Attia, Diana Van Heemst, Eero Kajantie, Rossella Sorice, Giovanni Gambaro, Robert A. Scott, Andrew A. Hicks, Luigi Ferrucci, Marie Standl, Cecilia M. Lindgren, John M. Starr, Magnus Karlsson, Lars Lind, Jun Z. Li, John C. Chambers, Trevor A. Mori, Eco J. C. N. de Geus, Andrew C. Heath, Nicholas G. Martin, Juha Auvinen, Brendan M. Buckley, Anton J. M. de Craen, Melanie Waldenberger, Konstantin Strauch, Thomas Meitinger, Rodney J. Scott, Mark McEvoy, Marian Beekman, Cristina Bombieri, Paul M. Ridker, Karen L. Mohlke, Nancy L. Pedersen, Alanna C. Morrison, Dorret I. Boomsma, John B. Whitfield, David P. Strachan, Albert Hofman, Peter Vollenweider, Francesco Cucca, Marjo-Riitta Jarvelin, J. Wouter Jukema, Tim D. Spector, Anders Hamsten, Tanja Zeller, Andre G. Uitterlinden, Matthias Nauck, Vilmundur Gudnason, Lu Qi, Harald Grallert, Ingrid B. Borecki, Jerome I. Rotter, Winfried Maerz, Philipp S. Wild, Marja-Liisa Lokki, Michael Boyle, Veikko Salomaa, Mads Melbye, Johan G. Eriksson, James F. Wilson, Brenda W. J. H. Penninx, Diane M. Becker, Bradford B. Worrall, Greg Gibson, Ronald M. Krauss, Marina Ciullo, Gianluigi Zaza, Nicholas J. Wareham, Albertine J. Oldehinkel, Lyle J. Palmer, Sarah S. Murray, Peter P. Pramstaller, Stefania Bandinelli, Joachim Heinrich, Erik Ingelsson, Ian J. Deary, Reedik Magi, Liesbeth Vandenput, Pim van der Harst, Karl C. Desch, Jaspal S. Kooner, Claes Ohlsson, Caroline Hayward, Terho Lehtimaki, Alan R. Shuldiner, Donna K. Arnett, Lawrence J. Beilin, Antonietta Robino, Philippe Froguel, Mario Pirastu, Tine Jess, Wolfgang Koenig, Ruth J. F. Loos, Denis A. Evans, Helena Schmidt, George Davey Smith, P. Eline Slagboom, Gudny Eiriksdottir, Andrew P. Morris, Bruce M. Psaty, Russell P. Tracy, Ilja M. Nolte, Eric Boerwinkle, Sophie Visvikis-Siest, Alex P. Reiner, Myron Gross, Joshua C. Bis, Lude Franke, Oscar H. Franco, Emelia J. Benjamin, Daniel I. Chasman, Josee Dupuis, Harold Snieder, Abbas Dehghan, Behrooz Z. Alizadeh

Institut for Klinisk Medicin

71 Citationer (Scopus)

Originalsprog	Engelsk
Tidsskrift	American Journal of Human Genetics
Vol/bind	103
Udgave nummer	5
Sider (fra-til)	691-706
ISSN	0002-9297
DOI	https://doi.org/10.1016/j.ajhg.2018.09.009
Status	Udgivet - 1 nov. 2018

Adgang til dokumentet

10.1016/j.ajhg.2018.09.009

http://europepmc.org/articles/pmc6218410?pdf=render

Citationsformater

Ligthart, S., Vaez, A., Vosa, U., Stathopoulou, M. G., de Vries, P. S., Prins, B. P., Van der Most, P. J., Tanaka, T., Naderi, E., Rose, L. M., Wu, Y., Karlsson, R., Barbalic, M., Lin, H., Pool, R., Zhu, G., Mace, A., Sidore, C., Trompet, S., ... Alizadeh, B. Z. (2018). Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. American Journal of Human Genetics, 103(5), 691-706. https://doi.org/10.1016/j.ajhg.2018.09.009

Ligthart, S, Vaez, A, Vosa, U, Stathopoulou, MG, de Vries, PS, Prins, BP, Van der Most, PJ, Tanaka, T, Naderi, E, Rose, LM, Wu, Y, Karlsson, R, Barbalic, M, Lin, H, Pool, R, Zhu, G, Mace, A, Sidore, C, Trompet, S, Mangino, M, Sabater-Lleal, M, Kemp, JP, Abbasi, A, Kacprowski, T, Verweij, N, Smith, AV, Huang, T, Marzi, C, Feitosa, MF, Lohman, KK, Kleber, ME, Milaneschi, Y, Mueller, C, Huq, M, Vlachopoulou, E, Lyytikainen, L-P, Oldmeadow, C, Deelen, J, Perola, M, Zhao, J, Feenstra, B, Amini, M, Lahti, J, Schraut, KE, Fornage, M, Suktitipat, B, Chen, W-M, Li, X, Nutile, T, Malerba, G, Luan, J, Bak, T, Schork, N, Del Greco, FM, Thiering, E, Mahajan, A, Marioni, RE, Mihailov, E, Eriksson, J, Ozel, AB, Zhang, W, Nethander, M, Cheng, Y-C, Aslibekyan, S, Ang, W, Gandin, I, Yengo, L, Portas, L, Kooperberg, C, Hofer, E, Rajan, KB, Schurmann, C, den Hollander, W, Ahluwalia, TS, Zhao, J, Draisma, HHM, Ford, I, Timpson, N, Teumer, A, Huang, H, Wahl, S, Liu, Y, Huang, J, Uh, H-W, Geller, F, Joshi, PK, Yanek, LR, Trabetti, E, Lehne, B, Vozzi, D, Verbanck, M, Biino, G, Saba, Y, Meulenbelt, I, O'Connell, JR, Laakso, M, Giulianini, F, Magnusson, PKE, Ballantyne, CM, Hottenga, JJ, Montgomery, G, Rivadineira, F, Rueedi, R, Steri, M, Herzig, K-H, Stott, DJ, Menni, C, Franberg, M, St Pourcain, B, Felix, SB, Pers, TH, Bakker, SJL, Kraft, P, Peters, A, Vaidya, D, Delgado, G, Smit, JH, Grossmann, V, Sinisalo, J, Seppala, I, Williams, SR, Holliday, EG, Moed, M, Langenberg, C, Raikkonen, K, Ding, J, Campbell, H, Sale, MM, Chen, Y-DI, James, AL, Ruggiero, D, Soranzo, N, Hartman, CA, Smith, EN, Berenson, GS, Fuchsberger, C, Hernandez, D, Tiesler, CMT, Giedraitis, V, Liewald, D, Fischer, K, Mellstrom, D, Larsson, A, Wang, Y, Scott, WR, Lorentzon, M, Beilby, J, Ryan, KA, Pennell, CE, Vuckovic, D, Balkau, B, Concas, MP, Schmidt, R, de Leon, CFM, Bottinger, EP, Kloppenburg, M, Paternoster, L, Boehnke, M, Musk, AW, Willemsen, G, Evans, DM, Madden, PAF, Kahonen, M, Kutalik, Z, Zoledziewska, M, Karhunen, V, Kritchevsky, SB, Sattar, N, Lachance, G, Clarke, R, Harris, TB, Raitakari, OT, Attia, JR, Van Heemst, D, Kajantie, E, Sorice, R, Gambaro, G, Scott, RA, Hicks, AA, Ferrucci, L, Standl, M, Lindgren, CM, Starr, JM, Karlsson, M, Lind, L, Li, JZ, Chambers, JC, Mori, TA, de Geus, EJCN, Heath, AC, Martin, NG, Auvinen, J, Buckley, BM, de Craen, AJM, Waldenberger, M, Strauch, K, Meitinger, T, Scott, RJ, McEvoy, M, Beekman, M, Bombieri, C, Ridker, PM, Mohlke, KL, Pedersen, NL, Morrison, AC, Boomsma, DI, Whitfield, JB, Strachan, DP, Hofman, A, Vollenweider, P, Cucca, F, Jarvelin, M-R, Jukema, JW, Spector, TD, Hamsten, A, Zeller, T, Uitterlinden, AG, Nauck, M, Gudnason, V, Qi, L, Grallert, H, Borecki, IB, Rotter, JI, Maerz, W, Wild, PS, Lokki, M-L, Boyle, M, Salomaa, V, Melbye, M, Eriksson, JG, Wilson, JF, Penninx, BWJH, Becker, DM, Worrall, BB, Gibson, G, Krauss, RM, Ciullo, M, Zaza, G, Wareham, NJ, Oldehinkel, AJ, Palmer, LJ, Murray, SS, Pramstaller, PP, Bandinelli, S, Heinrich, J, Ingelsson, E, Deary, IJ, Magi, R, Vandenput, L, van der Harst, P, Desch, KC, Kooner, JS, Ohlsson, C, Hayward, C, Lehtimaki, T, Shuldiner, AR, Arnett, DK, Beilin, LJ, Robino, A, Froguel, P, Pirastu, M, Jess, T, Koenig, W, Loos, RJF, Evans, DA, Schmidt, H, Smith, GD, Slagboom, PE, Eiriksdottir, G, Morris, AP, Psaty, BM, Tracy, RP, Nolte, IM, Boerwinkle, E, Visvikis-Siest, S, Reiner, AP, Gross, M, Bis, JC, Franke, L, Franco, OH, Benjamin, EJ, Chasman, DI, Dupuis, J, Snieder, H, Dehghan, A & Alizadeh, BZ 2018, 'Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders', American Journal of Human Genetics, bind 103, nr. 5, s. 691-706. https://doi.org/10.1016/j.ajhg.2018.09.009

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title = "Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders",

author = "Symen Ligthart and Ahmad Vaez and Urmo Vosa and Stathopoulou, {Maria G.} and {de Vries}, {Paul S.} and Prins, {Bram P.} and {Van der Most}, {Peter J.} and Toshiko Tanaka and Elnaz Naderi and Rose, {Lynda M.} and Ying Wu and Robert Karlsson and Maja Barbalic and Honghuang Lin and Rene Pool and Gu Zhu and Aurelien Mace and Carlo Sidore and Stella Trompet and Massimo Mangino and Maria Sabater-Lleal and Kemp, {John P.} and Ali Abbasi and Tim Kacprowski and Niek Verweij and Smith, {Albert V.} and Tao Huang and Carola Marzi and Feitosa, {Mary F.} and Lohman, {Kurt K.} and Kleber, {Marcus E.} and Yuri Milaneschi and Christian Mueller and Mahmudul Huq and Efthymia Vlachopoulou and Leo-Pekka Lyytikainen and Christopher Oldmeadow and Joris Deelen and Markus Perola and Jing Zhao and Bjarke Feenstra and Marzyeh Amini and Jari Lahti and Schraut, {Katharina E.} and Myriam Fornage and Bhoom Suktitipat and Wei-Min Chen and Xiaohui Li and Teresa Nutile and Giovanni Malerba and Jian'an Luan and Tom Bak and Nicholas Schork and {Del Greco}, {Fabiola M.} and Elisabeth Thiering and Anubha Mahajan and Marioni, {Riccardo E.} and Evelin Mihailov and Joel Eriksson and Ozel, {Ayse Bilge} and Weihua Zhang and Maria Nethander and Yu-Ching Cheng and Stella Aslibekyan and Wei Ang and Ilaria Gandin and Loic Yengo and Laura Portas and Charles Kooperberg and Edith Hofer and Rajan, {Kumar B.} and Claudia Schurmann and {den Hollander}, Wouter and Ahluwalia, {Tarunveer S.} and Jing Zhao and Draisma, {Harmen H. M.} and Ian Ford and Nicholas Timpson and Alexander Teumer and Hongyan Huang and Simone Wahl and YongMei Liu and Jie Huang and Hae-Won Uh and Frank Geller and Joshi, {Peter K.} and Yanek, {Lisa R.} and Elisabetta Trabetti and Benjamin Lehne and Diego Vozzi and Marie Verbanck and Ginevra Biino and Yasaman Saba and Ingrid Meulenbelt and O'Connell, {Jeff R.} and Markku Laakso and Franco Giulianini and Magnusson, {Patrik K. E.} and Ballantyne, {Christie M.} and Hottenga, {Jouke Jan} and GrantW. Montgomery and Fernando Rivadineira and Rico Rueedi and Maristella Steri and Karl-Heinz Herzig and Stott, {David J.} and Cristina Menni and Mattias Franberg and {St Pourcain}, Beate and Felix, {Stephan B.} and Pers, {Tune H.} and Bakker, {Stephan J. L.} and Peter Kraft and Annette Peters and Dhananjay Vaidya and Graciela Delgado and Smit, {Johannes H.} and Vera Grossmann and Juha Sinisalo and Ilkka Seppala and Williams, {Stephen R.} and Holliday, {Elizabeth G.} and Matthijs Moed and Claudia Langenberg and Katri Raikkonen and Jingzhong Ding and Harry Campbell and Sale, {Michele M.} and Chen, {Yii-Der I.} and James, {Alan L.} and Daniela Ruggiero and Nicole Soranzo and Hartman, {Catharina A.} and Smith, {Erin N.} and Berenson, {Gerald S.} and Christian Fuchsberger and Dena Hernandez and Tiesler, {Carla M. T.} and Vilmantas Giedraitis and David Liewald and Krista Fischer and Dan Mellstrom and Anders Larsson and Yunmei Wang and Scott, {William R.} and Matthias Lorentzon and John Beilby and Ryan, {Kathleen A.} and Pennell, {Craig E.} and Dragana Vuckovic and Beverly Balkau and Concas, {Maria Pina} and Reinhold Schmidt and {de Leon}, {Carlos F. Mendes} and Bottinger, {Erwin P.} and Margreet Kloppenburg and Lavinia Paternoster and Michael Boehnke and Musk, {A. W.} and Gonneke Willemsen and Evans, {David M.} and Madden, {Pamela A. F.} and Mika Kahonen and Zoltan Kutalik and Magdalena Zoledziewska and Ville Karhunen and Kritchevsky, {Stephen B.} and Naveed Sattar and Genevieve Lachance and Robert Clarke and Harris, {Tamara B.} and Raitakari, {Olli T.} and Attia, {John R.} and {Van Heemst}, Diana and Eero Kajantie and Rossella Sorice and Giovanni Gambaro and Scott, {Robert A.} and Hicks, {Andrew A.} and Luigi Ferrucci and Marie Standl and Lindgren, {Cecilia M.} and Starr, {John M.} and Magnus Karlsson and Lars Lind and Li, {Jun Z.} and Chambers, {John C.} and Mori, {Trevor A.} and {de Geus}, {Eco J. C. N.} and Heath, {Andrew C.} and Martin, {Nicholas G.} and Juha Auvinen and Buckley, {Brendan M.} and {de Craen}, {Anton J. M.} and Melanie Waldenberger and Konstantin Strauch and Thomas Meitinger and Scott, {Rodney J.} and Mark McEvoy and Marian Beekman and Cristina Bombieri and Ridker, {Paul M.} and Mohlke, {Karen L.} and Pedersen, {Nancy L.} and Morrison, {Alanna C.} and Boomsma, {Dorret I.} and Whitfield, {John B.} and Strachan, {David P.} and Albert Hofman and Peter Vollenweider and Francesco Cucca and Marjo-Riitta Jarvelin and Jukema, {J. Wouter} and Spector, {Tim D.} and Anders Hamsten and Tanja Zeller and Uitterlinden, {Andre G.} and Matthias Nauck and Vilmundur Gudnason and Lu Qi and Harald Grallert and Borecki, {Ingrid B.} and Rotter, {Jerome I.} and Winfried Maerz and Wild, {Philipp S.} and Marja-Liisa Lokki and Michael Boyle and Veikko Salomaa and Mads Melbye and Eriksson, {Johan G.} and Wilson, {James F.} and Penninx, {Brenda W. J. H.} and Becker, {Diane M.} and Worrall, {Bradford B.} and Greg Gibson and Krauss, {Ronald M.} and Marina Ciullo and Gianluigi Zaza and Wareham, {Nicholas J.} and Oldehinkel, {Albertine J.} and Palmer, {Lyle J.} and Murray, {Sarah S.} and Pramstaller, {Peter P.} and Stefania Bandinelli and Joachim Heinrich and Erik Ingelsson and Deary, {Ian J.} and Reedik Magi and Liesbeth Vandenput and {van der Harst}, Pim and Desch, {Karl C.} and Kooner, {Jaspal S.} and Claes Ohlsson and Caroline Hayward and Terho Lehtimaki and Shuldiner, {Alan R.} and Arnett, {Donna K.} and Beilin, {Lawrence J.} and Antonietta Robino and Philippe Froguel and Mario Pirastu and Tine Jess and Wolfgang Koenig and Loos, {Ruth J. F.} and Evans, {Denis A.} and Helena Schmidt and Smith, {George Davey} and Slagboom, {P. Eline} and Gudny Eiriksdottir and Morris, {Andrew P.} and Psaty, {Bruce M.} and Tracy, {Russell P.} and Nolte, {Ilja M.} and Eric Boerwinkle and Sophie Visvikis-Siest and Reiner, {Alex P.} and Myron Gross and Bis, {Joshua C.} and Lude Franke and Franco, {Oscar H.} and Benjamin, {Emelia J.} and Chasman, {Daniel I.} and Josee Dupuis and Harold Snieder and Abbas Dehghan and Alizadeh, {Behrooz Z.}",

year = "2018",

month = nov,

day = "1",

doi = "10.1016/j.ajhg.2018.09.009",

language = "English",

volume = "103",

pages = "691--706",

journal = "American Journal of Human Genetics",

issn = "0002-9297",

publisher = "Cell Press",

number = "5",

}

TY - JOUR

T1 - Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

AU - Ligthart, Symen

AU - Vaez, Ahmad

AU - Vosa, Urmo

AU - Stathopoulou, Maria G.

AU - de Vries, Paul S.

AU - Prins, Bram P.

AU - Van der Most, Peter J.

AU - Tanaka, Toshiko

AU - Naderi, Elnaz

AU - Rose, Lynda M.

AU - Wu, Ying

AU - Karlsson, Robert

AU - Barbalic, Maja

AU - Lin, Honghuang

AU - Pool, Rene

AU - Zhu, Gu

AU - Mace, Aurelien

AU - Sidore, Carlo

AU - Trompet, Stella

AU - Mangino, Massimo

AU - Sabater-Lleal, Maria

AU - Kemp, John P.

AU - Abbasi, Ali

AU - Kacprowski, Tim

AU - Verweij, Niek

AU - Smith, Albert V.

AU - Huang, Tao

AU - Marzi, Carola

AU - Feitosa, Mary F.

AU - Lohman, Kurt K.

AU - Kleber, Marcus E.

AU - Milaneschi, Yuri

AU - Mueller, Christian

AU - Huq, Mahmudul

AU - Vlachopoulou, Efthymia

AU - Lyytikainen, Leo-Pekka

AU - Oldmeadow, Christopher

AU - Deelen, Joris

AU - Perola, Markus

AU - Zhao, Jing

AU - Feenstra, Bjarke

AU - Amini, Marzyeh

AU - Lahti, Jari

AU - Schraut, Katharina E.

AU - Fornage, Myriam

AU - Suktitipat, Bhoom

AU - Chen, Wei-Min

AU - Li, Xiaohui

AU - Nutile, Teresa

AU - Malerba, Giovanni

AU - Luan, Jian'an

AU - Bak, Tom

AU - Schork, Nicholas

AU - Del Greco, Fabiola M.

AU - Thiering, Elisabeth

AU - Mahajan, Anubha

AU - Marioni, Riccardo E.

AU - Mihailov, Evelin

AU - Eriksson, Joel

AU - Ozel, Ayse Bilge

AU - Zhang, Weihua

AU - Nethander, Maria

AU - Cheng, Yu-Ching

AU - Aslibekyan, Stella

AU - Ang, Wei

AU - Gandin, Ilaria

AU - Yengo, Loic

AU - Portas, Laura

AU - Kooperberg, Charles

AU - Hofer, Edith

AU - Rajan, Kumar B.

AU - Schurmann, Claudia

AU - den Hollander, Wouter

AU - Ahluwalia, Tarunveer S.

AU - Zhao, Jing

AU - Draisma, Harmen H. M.

AU - Ford, Ian

AU - Timpson, Nicholas

AU - Teumer, Alexander

AU - Huang, Hongyan

AU - Wahl, Simone

AU - Liu, YongMei

AU - Huang, Jie

AU - Uh, Hae-Won

AU - Geller, Frank

AU - Joshi, Peter K.

AU - Yanek, Lisa R.

AU - Trabetti, Elisabetta

AU - Lehne, Benjamin

AU - Vozzi, Diego

AU - Verbanck, Marie

AU - Biino, Ginevra

AU - Saba, Yasaman

AU - Meulenbelt, Ingrid

AU - O'Connell, Jeff R.

AU - Laakso, Markku

AU - Giulianini, Franco

AU - Magnusson, Patrik K. E.

AU - Ballantyne, Christie M.

AU - Hottenga, Jouke Jan

AU - Montgomery, GrantW.

AU - Rivadineira, Fernando

AU - Rueedi, Rico

AU - Steri, Maristella

AU - Herzig, Karl-Heinz

AU - Stott, David J.

AU - Menni, Cristina

AU - Franberg, Mattias

AU - St Pourcain, Beate

AU - Felix, Stephan B.

AU - Pers, Tune H.

AU - Bakker, Stephan J. L.

AU - Kraft, Peter

AU - Peters, Annette

AU - Vaidya, Dhananjay

AU - Delgado, Graciela

AU - Smit, Johannes H.

AU - Grossmann, Vera

AU - Sinisalo, Juha

AU - Seppala, Ilkka

AU - Williams, Stephen R.

AU - Holliday, Elizabeth G.

AU - Moed, Matthijs

AU - Langenberg, Claudia

AU - Raikkonen, Katri

AU - Ding, Jingzhong

AU - Campbell, Harry

AU - Sale, Michele M.

AU - Chen, Yii-Der I.

AU - James, Alan L.

AU - Ruggiero, Daniela

AU - Soranzo, Nicole

AU - Hartman, Catharina A.

AU - Smith, Erin N.

AU - Berenson, Gerald S.

AU - Fuchsberger, Christian

AU - Hernandez, Dena

AU - Tiesler, Carla M. T.

AU - Giedraitis, Vilmantas

AU - Liewald, David

AU - Fischer, Krista

AU - Mellstrom, Dan

AU - Larsson, Anders

AU - Wang, Yunmei

AU - Scott, William R.

AU - Lorentzon, Matthias

AU - Beilby, John

AU - Ryan, Kathleen A.

AU - Pennell, Craig E.

AU - Vuckovic, Dragana

AU - Balkau, Beverly

AU - Concas, Maria Pina

AU - Schmidt, Reinhold

AU - de Leon, Carlos F. Mendes

AU - Bottinger, Erwin P.

AU - Kloppenburg, Margreet

AU - Paternoster, Lavinia

AU - Boehnke, Michael

AU - Musk, A. W.

AU - Willemsen, Gonneke

AU - Evans, David M.

AU - Madden, Pamela A. F.

AU - Kahonen, Mika

AU - Kutalik, Zoltan

AU - Zoledziewska, Magdalena

AU - Karhunen, Ville

AU - Kritchevsky, Stephen B.

AU - Sattar, Naveed

AU - Lachance, Genevieve

AU - Clarke, Robert

AU - Harris, Tamara B.

AU - Raitakari, Olli T.

AU - Attia, John R.

AU - Van Heemst, Diana

AU - Kajantie, Eero

AU - Sorice, Rossella

AU - Gambaro, Giovanni

AU - Scott, Robert A.

AU - Hicks, Andrew A.

AU - Ferrucci, Luigi

AU - Standl, Marie

AU - Lindgren, Cecilia M.

AU - Starr, John M.

AU - Karlsson, Magnus

AU - Lind, Lars

AU - Li, Jun Z.

AU - Chambers, John C.

AU - Mori, Trevor A.

AU - de Geus, Eco J. C. N.

AU - Heath, Andrew C.

AU - Martin, Nicholas G.

AU - Auvinen, Juha

AU - Buckley, Brendan M.

AU - de Craen, Anton J. M.

AU - Waldenberger, Melanie

AU - Strauch, Konstantin

AU - Meitinger, Thomas

AU - Scott, Rodney J.

AU - McEvoy, Mark

AU - Beekman, Marian

AU - Bombieri, Cristina

AU - Ridker, Paul M.

AU - Mohlke, Karen L.

AU - Pedersen, Nancy L.

AU - Morrison, Alanna C.

AU - Boomsma, Dorret I.

AU - Whitfield, John B.

AU - Strachan, David P.

AU - Hofman, Albert

AU - Vollenweider, Peter

AU - Cucca, Francesco

AU - Jarvelin, Marjo-Riitta

AU - Jukema, J. Wouter

AU - Spector, Tim D.

AU - Hamsten, Anders

AU - Zeller, Tanja

AU - Uitterlinden, Andre G.

AU - Nauck, Matthias

AU - Gudnason, Vilmundur

AU - Qi, Lu

AU - Grallert, Harald

AU - Borecki, Ingrid B.

AU - Rotter, Jerome I.

AU - Maerz, Winfried

AU - Wild, Philipp S.

AU - Lokki, Marja-Liisa

AU - Boyle, Michael

AU - Salomaa, Veikko

AU - Melbye, Mads

AU - Eriksson, Johan G.

AU - Wilson, James F.

AU - Penninx, Brenda W. J. H.

AU - Becker, Diane M.

AU - Worrall, Bradford B.

AU - Gibson, Greg

AU - Krauss, Ronald M.

AU - Ciullo, Marina

AU - Zaza, Gianluigi

AU - Wareham, Nicholas J.

AU - Oldehinkel, Albertine J.

AU - Palmer, Lyle J.

AU - Murray, Sarah S.

AU - Pramstaller, Peter P.

AU - Bandinelli, Stefania

AU - Heinrich, Joachim

AU - Ingelsson, Erik

AU - Deary, Ian J.

AU - Magi, Reedik

AU - Vandenput, Liesbeth

AU - van der Harst, Pim

AU - Desch, Karl C.

AU - Kooner, Jaspal S.

AU - Ohlsson, Claes

AU - Hayward, Caroline

AU - Lehtimaki, Terho

AU - Shuldiner, Alan R.

AU - Arnett, Donna K.

AU - Beilin, Lawrence J.

AU - Robino, Antonietta

AU - Froguel, Philippe

AU - Pirastu, Mario

AU - Jess, Tine

AU - Koenig, Wolfgang

AU - Loos, Ruth J. F.

AU - Evans, Denis A.

AU - Schmidt, Helena

AU - Smith, George Davey

AU - Slagboom, P. Eline

AU - Eiriksdottir, Gudny

AU - Morris, Andrew P.

AU - Psaty, Bruce M.

AU - Tracy, Russell P.

AU - Nolte, Ilja M.

AU - Boerwinkle, Eric

AU - Visvikis-Siest, Sophie

AU - Reiner, Alex P.

AU - Gross, Myron

AU - Bis, Joshua C.

AU - Franke, Lude

AU - Franco, Oscar H.

AU - Benjamin, Emelia J.

AU - Chasman, Daniel I.

AU - Dupuis, Josee

AU - Snieder, Harold

AU - Dehghan, Abbas

AU - Alizadeh, Behrooz Z.

PY - 2018/11/1

Y1 - 2018/11/1

U2 - 10.1016/j.ajhg.2018.09.009

DO - 10.1016/j.ajhg.2018.09.009

M3 - Journal article

C2 - 30388399

SN - 0002-9297

VL - 103

SP - 691

EP - 706

JO - American Journal of Human Genetics

JF - American Journal of Human Genetics

IS - 5

ER -

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

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