Generic single-channel detection of absence seizures

TY - JOUR

T1 - Generic single-channel detection of absence seizures

AU - Petersen, Eline B

AU - Duun-Henriksen, Jonas

AU - Mazzaretto, Andrea

AU - Kjær, Troels W

AU - Thomsen, Carsten E

AU - Sorensen, Helge B D

PY - 2011

Y1 - 2011

N2 - A long-term EEG-monitoring system, which automatically marks seizure events, is useful for diagnosing and treating epilepsy. A generic method utilizing the low inter-and intra-patient variabilities in EEG-characteristics during absence seizures is proposed. This paper investigates if the spike-and-wave behaviour during absence seizures is so distinct that a single-channel implementation is possible. 18 channels of scalp electroencephalography (EEG), from 19 patients suffering from childhood absence epilepsy, are analysed individually. The characteristics of the seizures are captured using the energy content of wavelet transform subbands and classified using a support vector machine. To ease the evaluation of the method, we present a new graphical visualization of the performance based on the topographical distribution on the scalp. The presented seizure detection method shows that the best result is obtained for the derivation F7-FP1. Using this channel a sensitivity of 99.1 %, positive predictive value of 94.8 %, mean detection latency of 3.7 s, and false detection rate value of 0.5/h was obtained. The topographical visualization of the results clearly shows that the frontal, midline, and parietal channels outperform detection based on the channels in the occipital region.

AB - A long-term EEG-monitoring system, which automatically marks seizure events, is useful for diagnosing and treating epilepsy. A generic method utilizing the low inter-and intra-patient variabilities in EEG-characteristics during absence seizures is proposed. This paper investigates if the spike-and-wave behaviour during absence seizures is so distinct that a single-channel implementation is possible. 18 channels of scalp electroencephalography (EEG), from 19 patients suffering from childhood absence epilepsy, are analysed individually. The characteristics of the seizures are captured using the energy content of wavelet transform subbands and classified using a support vector machine. To ease the evaluation of the method, we present a new graphical visualization of the performance based on the topographical distribution on the scalp. The presented seizure detection method shows that the best result is obtained for the derivation F7-FP1. Using this channel a sensitivity of 99.1 %, positive predictive value of 94.8 %, mean detection latency of 3.7 s, and false detection rate value of 0.5/h was obtained. The topographical visualization of the results clearly shows that the frontal, midline, and parietal channels outperform detection based on the channels in the occipital region.

KW - Electroencephalography

KW - Epilepsy, Absence

KW - Female

KW - Humans

KW - Male

U2 - 10.1109/IEMBS.2011.6091194

DO - 10.1109/IEMBS.2011.6091194

M3 - Journal article

C2 - 22255417

SN - 0589-1019

VL - 2011

SP - 4820

EP - 4823

JO - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

JF - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

ER -