@article{6dd34d87398b493baa6d5fc7ae792284,
title = "Generation of spinocerebellar ataxia type 2 patient-derived iPSC line H271",
abstract = "Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disease primarily affecting the cerebellum. Very little is known about the molecular mechanisms underlying the disease and, to date, no cure or treatment is available. Here, we demonstrate the generation of an induced pluripotent stem cell (iPSC) line of a SCA2 patient. The selected clone has been proven to be a bona fide iPSC line, which retains a normal karyotype. Due to its differentiation potential into neurons, this iPSC line will be a valuable tool in studying a disease-specific phenotype of SCA2.",
keywords = "Alleles, Ataxin-2, Base Sequence, Cell Differentiation, Cell Line, Cellular Reprogramming, Humans, Induced Pluripotent Stem Cells, Karyotype, Male, Molecular Sequence Data, Plasmids, Sequence Analysis, DNA, Spinocerebellar Ataxias, Transcription Factors, Transfection, Journal Article, Research Support, Non-U.S. Gov't",
author = "Marthaler, {Adele Gabriele} and Alisa Tubsuwan and Benjamin Schmid and Poulsen, {Ulla B.} and Poul Hyttel and Nielsen, {J{\o}rgen Erik} and Nielsen, {Troels Tolstrup} and Bj{\o}rn Holst",
note = "Copyright {\textcopyright} 2015. Published by Elsevier B.V.",
year = "2016",
month = jan,
day = "1",
doi = "10.1016/j.scr.2015.12.027",
language = "English",
volume = "16",
pages = "159--161",
journal = "Stem Cell Research",
issn = "1873-5061",
publisher = "Elsevier",
number = "1",
}