Gallbladder emptying and cholecystokinin response to fish oil and trioleate ingestion

C Riber; L Hojgaard; J L Madsen; J F Rehfeld; O Olsen

Gallbladder emptying and cholecystokinin response to fish oil and trioleate ingestion

C Riber, L Hojgaard, J L Madsen, J F Rehfeld, O Olsen

8 Citationer (Scopus)

Abstract

The aim of the present study was to compare gallbladder emptying, gastric emptying and release of cholecystokinin (CCK), gastrin and secretin after intragastric administration of fish oil and trioleate. After intravenous injection of 99mTc-HIDA, 30 ml of a lipid labelled with 111In was administered through a gastric tube. Using dual scintigraphy with two markers, gallbladder and gastric emptying were measured simultaneously for 120 min. Plasma concentrations of gastrin, secretin and CCK, were determined throughout the period. The emptying of the gallbladder was reduced by 27% and the release of CCK by 85% after fish oil as compared with trioleate. Gastric emptying as well as the release of gastrin and secretin were similar after the two types of fat. The results suggest that the reduced gallbladder emptying after fish oil may be due to a smaller release of CCK.

Originalsprog	Engelsk
Tidsskrift	Digestion
Vol/bind	57
Udgave nummer	3
Sider (fra-til)	161-4
Antal sider	4
ISSN	0012-2823
Status	Udgivet - 1996

Citationsformater

@article{31efe375245c4e458fd38e63c3302e16,

title = "Gallbladder emptying and cholecystokinin response to fish oil and trioleate ingestion",

abstract = "The aim of the present study was to compare gallbladder emptying, gastric emptying and release of cholecystokinin (CCK), gastrin and secretin after intragastric administration of fish oil and trioleate. After intravenous injection of 99mTc-HIDA, 30 ml of a lipid labelled with 111In was administered through a gastric tube. Using dual scintigraphy with two markers, gallbladder and gastric emptying were measured simultaneously for 120 min. Plasma concentrations of gastrin, secretin and CCK, were determined throughout the period. The emptying of the gallbladder was reduced by 27% and the release of CCK by 85% after fish oil as compared with trioleate. Gastric emptying as well as the release of gastrin and secretin were similar after the two types of fat. The results suggest that the reduced gallbladder emptying after fish oil may be due to a smaller release of CCK.",

keywords = "Adult, Cholecystokinin, Fatty Acids, Omega-3, Fish Oils, Gallbladder Emptying, Gastric Emptying, Gastrins, Humans, Imino Acids, Indium Radioisotopes, Male, Organotechnetium Compounds, Radioimmunoassay, Secretin, Technetium Tc 99m Lidofenin, Triolein, Comparative Study, Journal Article",

author = "C Riber and L Hojgaard and Madsen, {J L} and Rehfeld, {J F} and O Olsen",

year = "1996",

language = "English",

volume = "57",

pages = "161--4",

journal = "Digestion",

issn = "0012-2823",

publisher = "S Karger AG",

number = "3",

}

TY - JOUR

T1 - Gallbladder emptying and cholecystokinin response to fish oil and trioleate ingestion

AU - Riber, C

AU - Hojgaard, L

AU - Madsen, J L

AU - Rehfeld, J F

AU - Olsen, O

PY - 1996

Y1 - 1996

N2 - The aim of the present study was to compare gallbladder emptying, gastric emptying and release of cholecystokinin (CCK), gastrin and secretin after intragastric administration of fish oil and trioleate. After intravenous injection of 99mTc-HIDA, 30 ml of a lipid labelled with 111In was administered through a gastric tube. Using dual scintigraphy with two markers, gallbladder and gastric emptying were measured simultaneously for 120 min. Plasma concentrations of gastrin, secretin and CCK, were determined throughout the period. The emptying of the gallbladder was reduced by 27% and the release of CCK by 85% after fish oil as compared with trioleate. Gastric emptying as well as the release of gastrin and secretin were similar after the two types of fat. The results suggest that the reduced gallbladder emptying after fish oil may be due to a smaller release of CCK.

AB - The aim of the present study was to compare gallbladder emptying, gastric emptying and release of cholecystokinin (CCK), gastrin and secretin after intragastric administration of fish oil and trioleate. After intravenous injection of 99mTc-HIDA, 30 ml of a lipid labelled with 111In was administered through a gastric tube. Using dual scintigraphy with two markers, gallbladder and gastric emptying were measured simultaneously for 120 min. Plasma concentrations of gastrin, secretin and CCK, were determined throughout the period. The emptying of the gallbladder was reduced by 27% and the release of CCK by 85% after fish oil as compared with trioleate. Gastric emptying as well as the release of gastrin and secretin were similar after the two types of fat. The results suggest that the reduced gallbladder emptying after fish oil may be due to a smaller release of CCK.

KW - Adult

KW - Cholecystokinin

KW - Fatty Acids, Omega-3

KW - Fish Oils

KW - Gallbladder Emptying

KW - Gastric Emptying

KW - Gastrins

KW - Humans

KW - Imino Acids

KW - Indium Radioisotopes

KW - Male

KW - Organotechnetium Compounds

KW - Radioimmunoassay

KW - Secretin

KW - Technetium Tc 99m Lidofenin

KW - Triolein

KW - Comparative Study

KW - Journal Article

M3 - Journal article

C2 - 8739088

SN - 0012-2823

VL - 57

SP - 161

EP - 164

JO - Digestion

JF - Digestion

IS - 3

ER -

Gallbladder emptying and cholecystokinin response to fish oil and trioleate ingestion

Abstract

Fingeraftryk

Citationsformater