Keyphrases
Ligand-gated Ion Channel
100%
Functional Characterization
100%
Nematodes
100%
Neurotransmitters
100%
L-glutamine
60%
Channel Opening
60%
Native-like
40%
Molecular Dynamics Simulation
20%
Anesthetic Agents
20%
Pharmacology
20%
Ivermectin
20%
GABAA Receptor (GABAAR)
20%
Multiple States
20%
Caenorhabditis Elegans
20%
Vertebrates
20%
Xenopus Oocytes
20%
Site-directed mutation
20%
Neurotransmitter Receptors
20%
Allosteric Modulation
20%
Ion Channels
20%
Pharmacological Significance
20%
Activation Property
20%
Ligand-gated
20%
Structural Information
20%
Anesthetics
20%
Extracellular Domain
20%
Human Membrane Proteins
20%
Concentration-dependent
20%
Site-directed mutagenesis
20%
Ligand Binding
20%
Conformational Change
20%
Agonism
20%
Allosteric Modulator
20%
Classical Activation
20%
Functional Relevance
20%
Benzodiazepines
20%
Structure Function
20%
Ethanol
20%
Pentameric Ligand-gated Ion Channel (pLGIC)
20%
Synaptic Transmission
20%
Modulatory Properties
20%
Drug Discovery
20%
Transmembrane Domain
20%
Anticonvulsant
20%
Alcohol
20%
Two-electrode Voltage-clamp Electrophysiology
20%
Channel Gating
20%
Biochemistry, Genetics and Molecular Biology
Nematode
100%
Ligand-Gated Ion Channel
100%
Neurotransmitter
100%
Glutamic Acid
100%
Chloride Channel
62%
GABAA Receptor
25%
Transmembrane Domain
12%
Electrophysiology
12%
Xenopus
12%
Caenorhabditis elegans
12%
Neurotransmitter Receptor
12%
Site-Directed Mutagenesis
12%
Conformational Change
12%
Synaptic Transmission
12%
Ion Channel
12%
Computer Simulation
12%
Voltage Clamp
12%
Ligand Binding
12%
Crystal Structure
12%
Neuroscience
Ligand-Gated Ion Channel
100%
Neurotransmitter
100%
Glutamic Acid
100%
Chloride Channel
62%
Receptor
37%
GABAA Receptor
25%
Anaesthetic
12%
Anticonvulsant
12%
Neurotransmitter Receptor
12%
Ion Channel
12%
Ligand Binding
12%
Electrophysiology
12%
Ivermectin
12%
Voltage Clamp
12%
Site-Directed Mutagenesis
12%
Synaptic Transmission
12%
Caenorhabditis elegans
12%