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From three-dimensional GPCR structure to rational ligand discovery
Albert J. Kooistra
, Rob Leurs, Iwan J.P. De Esch, Chris De Graaf
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31
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Keyphrases
Binding Mode
33%
Design Study
33%
Discovery-based
33%
G Protein-coupled Receptor
33%
GPCR Structure
100%
Ligand Design
33%
Ligand Discovery
100%
Ligand Structure
33%
Novel Ligands
66%
Protein Family
33%
Receptor Model
33%
Receptor Structure
33%
Screening Design
33%
Screening Process
33%
Signaling Pathway
33%
Structure Optimization
33%
Structure-based Ligand Design
33%
Structure-based Virtual Screening
66%
Three-dimensional (3D)
100%
Virtual Screening
100%
Virtual Screening Workflows
33%
Virtual Structure
33%
Biochemistry, Genetics and Molecular Biology
Crystal Structure
16%
G Protein Coupled Receptor
100%
Ligand Binding
16%
Protein Family
16%