@article{c47b38b0cbc111dea1f3000ea68e967b,
title = "Four newly isolated fuselloviruses from extreme geothermal environments reveal unusual morphologies and a possible interviral recombination mechanism",
abstract = "Spindle-shaped virus-like particles are abundant in extreme geothermal environments, from which five spindle-shaped viral species have been isolated to date. They infect members of the hyperthermophilic archaeal genus Sulfolobus, and constitute the Fuselloviridae, a family of double-stranded DNA viruses. Here we present four new members of this family, all from terrestrial acidic hot springs. Two of the new viruses exhibit a novel morphotype for their proposed attachment structures, and specific features of their genome sequences strongly suggest the identity of the host-attachment protein. All fuselloviral genomes are highly conserved at the nucleotide level, although the regions of conservation differ between virus-pairs, consistent with a high frequency of homologous recombination having occurred between them. We propose a fuselloviral specific mechanism for interviral recombination, and show that the spacers of the Sulfolobus CRISPR antiviral system are not biased to the highly similar regions of the fusellovirus genomes.",
author = "Peter Redder and Xu Peng and Kim Br{\"u}gger and Shah, {Shiraz Ali} and Ferdinand Roesch and Bo Greve and Qunxin She and Christa Schleper and Patrick Forterre and Garrett, {Roger A} and David Prangishvili",
year = "2009",
doi = "10.1111/j.1462-2920.2009.02009.x",
language = "English",
volume = "11",
pages = "2849--62",
journal = "Environmental Microbiology",
issn = "1462-2912",
publisher = "Wiley-Blackwell",
number = "11",
}