Forekomsten af komplementdefekter ved meningokoksygdom: Hvem skal undersøges?

TY - JOUR

T1 - Forekomsten af komplementdefekter ved meningokoksygdom

T2 - Hvem skal undersøges?

AU - Nielsen, H. E.

AU - Magnussen, P.

AU - Lind, I.

PY - 1991/1/1

Y1 - 1991/1/1

N2 - Congenital complement deficiency states occur very rarely. These deficiencies are associated with a high risk of meningococcal disease (MD). We suggest that the following groups of individuals with MD are examined for complement deficiencies: 1. Individuals belonging to families, in which more than one case of MD has occurred with an interval exceeding one month. 2. Individuals infected with the low-virulent meningococcal serogroups W-135, 29E, X, Y, Z. 3. Individuals with recurrent MD. Since properdin deficiency probably is the most common deficiency associated with MD it is important that the screening includes the alternative complement pathway.

AB - Congenital complement deficiency states occur very rarely. These deficiencies are associated with a high risk of meningococcal disease (MD). We suggest that the following groups of individuals with MD are examined for complement deficiencies: 1. Individuals belonging to families, in which more than one case of MD has occurred with an interval exceeding one month. 2. Individuals infected with the low-virulent meningococcal serogroups W-135, 29E, X, Y, Z. 3. Individuals with recurrent MD. Since properdin deficiency probably is the most common deficiency associated with MD it is important that the screening includes the alternative complement pathway.

UR - http://www.scopus.com/inward/record.url?scp=0026424771&partnerID=8YFLogxK

M3 - Review

C2 - 1902602

AN - SCOPUS:0026424771

SN - 0041-5782

VL - 153

SP - 1113

EP - 1116

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 16

ER -