Football training over 5 years is associated with preserved femoral bone mineral density in men with prostate cancer

TY - JOUR

T1 - Football training over 5 years is associated with preserved femoral bone mineral density in men with prostate cancer

AU - Uth, Jacob

AU - Fristrup, Bjørn

AU - Haahr, R D

AU - Brasso, Klaus

AU - Helge, Jørn Wulff

AU - Rørth, Mikael Rahbek

AU - Midtgaard, Julie

AU - Helge, Eva Wulff

AU - Krustrup, Peter

N1 - CURIS 2018 NEXS 257

PY - 2018/8

Y1 - 2018/8

N2 - This study investigated the association between long-term adherence to football training and retaining bone mineralization and physical capacity in men with prostate cancer (PCa) managed with androgen deprivation therapy (ADT). Patients completing follow-up at 32 weeks in the FC Prostate Randomized Controlled Trial (RCT) in 2012 or 2013 were invited to 5-year follow-up assessments in May 2017 (n = 30). Changes in physiological outcomes over time between the football participants (FTG) and nonparticipants (CON) were examined. Twenty-two men accepted the invitation of which 11, aged 71.3 ± 3.8 years, had continued to play self-organized football 1.7 (SD 0.5) times per week for 4½ years (±8 months). At 5 years, right femoral neck bone mineral density (BMD) had improved significantly in the FTG compared to CON (P =.028). No other significant between-group differences were observed. In FTG, RHR decreased by 4.3 bpm (P =.009) with no changes in CON. Muscle mass, knee-extensor muscle strength, VO2 max, and postural balance decreased in both groups. In FTG, the fraction of training time with HR between 80%-90% or >90% of HRmax was 29.9% (SD 20.6) and 22.8% (SD 28.7), respectively. Average distance covered during 3 × 20 minutes of football training was 2524 m (SD 525). Football training over a 5-year period was associated with preserved femoral neck BMD in elderly men with PCa managed on ADT. Intensity during football training was >80% of HRmax for 51% of training time after 5 years. Body composition and physical capacity deteriorated over 5 years regardless of football participation.

AB - This study investigated the association between long-term adherence to football training and retaining bone mineralization and physical capacity in men with prostate cancer (PCa) managed with androgen deprivation therapy (ADT). Patients completing follow-up at 32 weeks in the FC Prostate Randomized Controlled Trial (RCT) in 2012 or 2013 were invited to 5-year follow-up assessments in May 2017 (n = 30). Changes in physiological outcomes over time between the football participants (FTG) and nonparticipants (CON) were examined. Twenty-two men accepted the invitation of which 11, aged 71.3 ± 3.8 years, had continued to play self-organized football 1.7 (SD 0.5) times per week for 4½ years (±8 months). At 5 years, right femoral neck bone mineral density (BMD) had improved significantly in the FTG compared to CON (P =.028). No other significant between-group differences were observed. In FTG, RHR decreased by 4.3 bpm (P =.009) with no changes in CON. Muscle mass, knee-extensor muscle strength, VO2 max, and postural balance decreased in both groups. In FTG, the fraction of training time with HR between 80%-90% or >90% of HRmax was 29.9% (SD 20.6) and 22.8% (SD 28.7), respectively. Average distance covered during 3 × 20 minutes of football training was 2524 m (SD 525). Football training over a 5-year period was associated with preserved femoral neck BMD in elderly men with PCa managed on ADT. Intensity during football training was >80% of HRmax for 51% of training time after 5 years. Body composition and physical capacity deteriorated over 5 years regardless of football participation.

KW - Androgen deprivation therapy

KW - Bone mineral density

KW - Exercise intensity

KW - Long-term follow-up

KW - Physical activity

KW - Soccer

KW - Sport

U2 - 10.1111/sms.13242

DO - 10.1111/sms.13242

M3 - Journal article

C2 - 30001572

AN - SCOPUS:85050454441

SN - 0905-7188

VL - 28

SP - 61

EP - 73

JO - Scandinavian Journal of Medicine & Science in Sports

JF - Scandinavian Journal of Medicine & Science in Sports

IS - Suppl. 1

ER -