Fedmens genetik

Søren Morgenthaler Echwald; Philip Just Larsen; Oluf Borbye Pedersen; Thorkild I A Sørensen

Fedmens genetik

Søren Morgenthaler Echwald, Philip Just Larsen, Oluf Borbye Pedersen, Thorkild I A Sørensen

1 Citationer (Scopus)

Abstract

Although environmental factors clearly play a role, studies of twins and adoptees show that obesity is a familial trait which to a large degree can be ascribed to genetic factors. According to evolutionary models, obesity-causing variants may originally have had an evolutionary benefit, whereas in a modern environment they pose a risk. Despite a clear genetic cause, the molecular genetic variations underlying common forms of obesity are not clear. Out of many hundred candidates, only a few hold up, and only variations in the MC4R gene have been found with a prevalence which may lead to common forms of obesity.

Bidragets oversatte titel	The genetics of obesity
Originalsprog	Dansk
Tidsskrift	Ugeskrift for læger
Vol/bind	168
Udgave nummer	2
Sider (fra-til)	150-152
Antal sider	3
ISSN	0041-5782
Status	Udgivet - 2006

Emneord

Genetic Predisposition to Disease
Humans
Obesity

FN’s Verdensmål

Dette resultat bidrager til følgende verdensmål

Citationsformater

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abstract = "Although environmental factors clearly play a role, studies of twins and adoptees show that obesity is a familial trait which to a large degree can be ascribed to genetic factors. According to evolutionary models, obesity-causing variants may originally have had an evolutionary benefit, whereas in a modern environment they pose a risk. Despite a clear genetic cause, the molecular genetic variations underlying common forms of obesity are not clear. Out of many hundred candidates, only a few hold up, and only variations in the MC4R gene have been found with a prevalence which may lead to common forms of obesity.",

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TY - JOUR

T1 - Fedmens genetik

AU - Echwald, Søren Morgenthaler

AU - Larsen, Philip Just

AU - Pedersen, Oluf Borbye

AU - Sørensen, Thorkild I A

PY - 2006

Y1 - 2006

N2 - Although environmental factors clearly play a role, studies of twins and adoptees show that obesity is a familial trait which to a large degree can be ascribed to genetic factors. According to evolutionary models, obesity-causing variants may originally have had an evolutionary benefit, whereas in a modern environment they pose a risk. Despite a clear genetic cause, the molecular genetic variations underlying common forms of obesity are not clear. Out of many hundred candidates, only a few hold up, and only variations in the MC4R gene have been found with a prevalence which may lead to common forms of obesity.

AB - Although environmental factors clearly play a role, studies of twins and adoptees show that obesity is a familial trait which to a large degree can be ascribed to genetic factors. According to evolutionary models, obesity-causing variants may originally have had an evolutionary benefit, whereas in a modern environment they pose a risk. Despite a clear genetic cause, the molecular genetic variations underlying common forms of obesity are not clear. Out of many hundred candidates, only a few hold up, and only variations in the MC4R gene have been found with a prevalence which may lead to common forms of obesity.

KW - Genetic Predisposition to Disease

KW - Humans

KW - Obesity

M3 - Tidsskriftartikel

C2 - 16403338

SN - 0041-5782

VL - 168

SP - 150

EP - 152

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 2

ER -

Fedmens genetik

Abstract

Emneord

FN’s Verdensmål

Fingeraftryk

Citationsformater