Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development

Wei-Hung Pan; Felix Sommer; Maren Falk-Paulsen; Thomas Ulas; Philipp Best; Antonella Fazio; Priyadarshini Kachroo; Anne Luzius; Marlene Jentzsch; Ateequr Rehman; Fabian Mueller; Thomas Lengauer; Joern Walter; Sven Kuenzel; John F. Baines; Stefan Schreiber; Andre Franke; Joachim L. Schultze; Fredrik Backhed; Philip Rosenstiel

doi:10.1186/s13073-018-0534-5

Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development

Wei-Hung Pan, Felix Sommer, Maren Falk-Paulsen, Thomas Ulas, Philipp Best, Antonella Fazio, Priyadarshini Kachroo, Anne Luzius, Marlene Jentzsch, Ateequr Rehman, Fabian Mueller, Thomas Lengauer, Joern Walter, Sven Kuenzel, John F. Baines, Stefan Schreiber, Andre Franke, Joachim L. Schultze, Fredrik Backhed, Philip Rosenstiel

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Originalsprog	Engelsk
Artikelnummer	27
Tidsskrift	Genome Medicine
Vol/bind	10
Sider (fra-til)	1-15
ISSN	1756-994X
DOI	https://doi.org/10.1186/s13073-018-0534-5
Status	Udgivet - 13 apr. 2018

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10.1186/s13073-018-0534-5

Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal developmentForlagets udgivne version, 5,22 MB

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Pan, W.-H., Sommer, F., Falk-Paulsen, M., Ulas, T., Best, P., Fazio, A., Kachroo, P., Luzius, A., Jentzsch, M., Rehman, A., Mueller, F., Lengauer, T., Walter, J., Kuenzel, S., Baines, J. F., Schreiber, S., Franke, A., Schultze, J. L., Backhed, F., & Rosenstiel, P. (2018). Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development. Genome Medicine, 10, 1-15. Artikel 27. https://doi.org/10.1186/s13073-018-0534-5

Pan, W-H, Sommer, F, Falk-Paulsen, M, Ulas, T, Best, P, Fazio, A, Kachroo, P, Luzius, A, Jentzsch, M, Rehman, A, Mueller, F, Lengauer, T, Walter, J, Kuenzel, S, Baines, JF, Schreiber, S, Franke, A, Schultze, JL, Backhed, F & Rosenstiel, P 2018, 'Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development', Genome Medicine, bind 10, 27, s. 1-15. https://doi.org/10.1186/s13073-018-0534-5

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title = "Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development",

keywords = "Microbiota, Intestinal epithelial cell, Epigenetics, Methylation, Transcriptomics",

author = "Wei-Hung Pan and Felix Sommer and Maren Falk-Paulsen and Thomas Ulas and Philipp Best and Antonella Fazio and Priyadarshini Kachroo and Anne Luzius and Marlene Jentzsch and Ateequr Rehman and Fabian Mueller and Thomas Lengauer and Joern Walter and Sven Kuenzel and Baines, {John F.} and Stefan Schreiber and Andre Franke and Schultze, {Joachim L.} and Fredrik Backhed and Philip Rosenstiel",

year = "2018",

month = apr,

day = "13",

doi = "10.1186/s13073-018-0534-5",

language = "English",

volume = "10",

pages = "1--15",

journal = "Genome Medicine",

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TY - JOUR

T1 - Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development

AU - Pan, Wei-Hung

AU - Sommer, Felix

AU - Falk-Paulsen, Maren

AU - Ulas, Thomas

AU - Best, Philipp

AU - Fazio, Antonella

AU - Kachroo, Priyadarshini

AU - Luzius, Anne

AU - Jentzsch, Marlene

AU - Rehman, Ateequr

AU - Mueller, Fabian

AU - Lengauer, Thomas

AU - Walter, Joern

AU - Kuenzel, Sven

AU - Baines, John F.

AU - Schreiber, Stefan

AU - Franke, Andre

AU - Schultze, Joachim L.

AU - Backhed, Fredrik

AU - Rosenstiel, Philip

PY - 2018/4/13

Y1 - 2018/4/13

KW - Microbiota

KW - Intestinal epithelial cell

KW - Epigenetics

KW - Methylation

KW - Transcriptomics

U2 - 10.1186/s13073-018-0534-5

DO - 10.1186/s13073-018-0534-5

M3 - Journal article

C2 - 29653584

SN - 1756-994X

VL - 10

SP - 1

EP - 15

JO - Genome Medicine

JF - Genome Medicine

M1 - 27

ER -

Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development

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