TY - JOUR
T1 - Explaining psychological insulin resistance in adults with non-insulin-treated type 2 diabetes
T2 - The roles of diabetes distress and current medication concerns. Results from Diabetes MILES - Australia
AU - Holmes-Truscott, E.
AU - Skinner, T. C.
AU - Pouwer, F.
AU - Speight, J.
PY - 2016/2/1
Y1 - 2016/2/1
N2 - Aims To investigate the contribution of general and diabetes-specific emotional wellbeing and beliefs about medicines in the prediction of insulin therapy appraisals in adults with non-insulin-treated type 2 diabetes. Methods The sample included Diabetes MILES-Australia cross-sectional survey participants whose primary diabetes treatment was oral hypoglycaemic agents (N = 313; 49% women; mean ± SD age: 57 ± 9 years; diabetes duration: 7 ± 6 years). They completed validated measures of beliefs about the 'harm' and 'overuse' of medications in general (BMQ General); 'concerns' about and 'necessity' of current diabetes medications (BMQ Specific); negative insulin therapy appraisals (ITAS); depression (PHQ-9); anxiety (GAD-7), and diabetes distress (DDS-17). Factors associated with ITAS Negative scores were examined using hierarchical multiple regressions. Results Twenty-two percent of the variance in ITAS Negative scores (52 ± 10), was explained by: number of complications (β = -.15, p =.005), DDS-17 subscale 'emotional burden' (β =.23, p <.001), and 'concerns' about current diabetes treatment (β =.29, p <.001). General beliefs about medications and general emotional wellbeing did not contribute significantly to the model. Conclusions Psychological insulin resistance may reflect broader distress about diabetes and concerns about its treatment but not general beliefs about medicines, depression or anxiety. Reducing diabetes distress and current treatment concerns may improve attitudes towards insulin as a potential therapeutic option.
AB - Aims To investigate the contribution of general and diabetes-specific emotional wellbeing and beliefs about medicines in the prediction of insulin therapy appraisals in adults with non-insulin-treated type 2 diabetes. Methods The sample included Diabetes MILES-Australia cross-sectional survey participants whose primary diabetes treatment was oral hypoglycaemic agents (N = 313; 49% women; mean ± SD age: 57 ± 9 years; diabetes duration: 7 ± 6 years). They completed validated measures of beliefs about the 'harm' and 'overuse' of medications in general (BMQ General); 'concerns' about and 'necessity' of current diabetes medications (BMQ Specific); negative insulin therapy appraisals (ITAS); depression (PHQ-9); anxiety (GAD-7), and diabetes distress (DDS-17). Factors associated with ITAS Negative scores were examined using hierarchical multiple regressions. Results Twenty-two percent of the variance in ITAS Negative scores (52 ± 10), was explained by: number of complications (β = -.15, p =.005), DDS-17 subscale 'emotional burden' (β =.23, p <.001), and 'concerns' about current diabetes treatment (β =.29, p <.001). General beliefs about medications and general emotional wellbeing did not contribute significantly to the model. Conclusions Psychological insulin resistance may reflect broader distress about diabetes and concerns about its treatment but not general beliefs about medicines, depression or anxiety. Reducing diabetes distress and current treatment concerns may improve attitudes towards insulin as a potential therapeutic option.
KW - Beliefs about medications
KW - Diabetes distress
KW - Psychological insulin resistance
KW - Type 2 diabetes
UR - http://www.scopus.com/inward/record.url?scp=84954381804&partnerID=8YFLogxK
U2 - 10.1016/j.pcd.2015.06.006
DO - 10.1016/j.pcd.2015.06.006
M3 - Journal article
C2 - 26150327
AN - SCOPUS:84954381804
SN - 1751-9918
VL - 10
SP - 75
EP - 82
JO - Primary Care Diabetes
JF - Primary Care Diabetes
IS - 1
ER -
