Expert statement for the management of hypovolemia in sepsis

TY - JOUR

T1 - Expert statement for the management of hypovolemia in sepsis

AU - Perner, Anders

AU - Cecconi, Maurizio

AU - Cronhjort, Maria

AU - Darmon, Michael

AU - Jakob, Stephan M.

AU - Pettilä, Ville

AU - van der Horst, Iwan C.C.

PY - 2018

Y1 - 2018

N2 - Hypovolemia is frequent in patients with sepsis and may contribute to worse outcome. The management of these patients is impeded by the low quality of the evidence for many of the specific components of the care. In this paper, we discuss recent advances and controversies in this field and give expert statements for the management of hypovolemia in patients with sepsis including triggers and targets for fluid therapy and volumes and types of fluid to be given. Finally, we point to unanswered questions and suggest a roadmap for future research.

AB - Hypovolemia is frequent in patients with sepsis and may contribute to worse outcome. The management of these patients is impeded by the low quality of the evidence for many of the specific components of the care. In this paper, we discuss recent advances and controversies in this field and give expert statements for the management of hypovolemia in patients with sepsis including triggers and targets for fluid therapy and volumes and types of fluid to be given. Finally, we point to unanswered questions and suggest a roadmap for future research.

KW - Critical care

KW - Fluid therapy

KW - Hemodynamics

KW - Hypovolemia

KW - Sepsis

KW - Shock

U2 - 10.1007/s00134-018-5177-x

DO - 10.1007/s00134-018-5177-x

M3 - Review

C2 - 29696295

AN - SCOPUS:85046023505

SN - 0342-4642

VL - 44

SP - 791

EP - 798

JO - Intensive Care Medicine

JF - Intensive Care Medicine

IS - 6

ER -