Excitatory components of the mammalian locomotor CPG

TY - JOUR

T1 - Excitatory components of the mammalian locomotor CPG

AU - Kiehn, Ole

AU - Quinlan, Katharina A.

AU - Restrepo, Carlos Ernesto

AU - Lundfald, Line

AU - Borgius, Lotta

AU - Talpalar, Adolfo E.

AU - Endo, Toshiaki

PY - 2008/1/1

Y1 - 2008/1/1

N2 - Locomotion in mammals is to a large degree controlled directly by intrinsic spinal networks, called central pattern generators (CPGs). The overall function of these networks is governed by interaction between inhibitory and excitatory neurons. In the present review, we will discuss recent findings addressing the role of excitatory synaptic transmission for network function including the role of specific excitatory neuronal populations in coordinating muscle activity and in generating rhythmic activity.

AB - Locomotion in mammals is to a large degree controlled directly by intrinsic spinal networks, called central pattern generators (CPGs). The overall function of these networks is governed by interaction between inhibitory and excitatory neurons. In the present review, we will discuss recent findings addressing the role of excitatory synaptic transmission for network function including the role of specific excitatory neuronal populations in coordinating muscle activity and in generating rhythmic activity.

KW - Commissural interneuron

KW - Locomotion

KW - Motor neuron

KW - Spinal cord

KW - Transcription factor

UR - http://www.scopus.com/inward/record.url?scp=36749008469&partnerID=8YFLogxK

U2 - 10.1016/j.brainresrev.2007.07.002

DO - 10.1016/j.brainresrev.2007.07.002

M3 - Review

C2 - 17988744

AN - SCOPUS:36749008469

SN - 0006-8993

VL - 57

SP - 56

EP - 63

JO - Brain Research

JF - Brain Research

IS - 1

ER -