Evolutionary and biomedical insights from the rhesus macaque genome

Richard A Gibbs; Jeffrey Rogers; Michael G Katze; Roger Bumgarner; George M Weinstock; Elaine R Mardis; Karin A Remington; Robert L Strausberg; J Craig Venter; Richard K Wilson; Mark A Batzer; Carlos D Bustamante; Evan E Eichler; Matthew W Hahn; Ross C Hardison; Kateryna D Makova; Webb Miller; Aleksandar Milosavljevic; Robert E Palermo; Adam Siepel; James M Sikela; Tony Attaway; Stephanie Bell; Kelly E Bernard; Christian J Buhay; Mimi N Chandrabose; Marvin Dao; Clay Davis; Kimberly D Delehaunty; Yan Ding; Huyen H Dinh; Shannon Dugan-Rocha; Lucinda A Fulton; Ramatu Ayiesha Gabisi; Toni T Garner; Jennifer Godfrey; Alicia C Hawes; Judith Hernandez; Sandra Hines; Michael Holder; Jennifer Hume; Shalini N Jhangiani; Vandita Joshi; Ziad Mohid Khan; Ewen F Kirkness; Andrew Cree; R Gerald Fowler; Sandra Lee; Lora R Lewis; Rasmus Nielsen; Rhesus Macaque Genome Sequencing and Analysis Consortium

doi:10.1126/science.1139247

Evolutionary and biomedical insights from the rhesus macaque genome

Richard A Gibbs, Jeffrey Rogers, Michael G Katze, Roger Bumgarner, George M Weinstock, Elaine R Mardis, Karin A Remington, Robert L Strausberg, J Craig Venter, Richard K Wilson, Mark A Batzer, Carlos D Bustamante, Evan E Eichler, Matthew W Hahn, Ross C Hardison, Kateryna D Makova, Webb Miller, Aleksandar Milosavljevic, Robert E Palermo, Adam SiepelJames M Sikela, Tony Attaway, Stephanie Bell, Kelly E Bernard, Christian J Buhay, Mimi N Chandrabose, Marvin Dao, Clay Davis, Kimberly D Delehaunty, Yan Ding, Huyen H Dinh, Shannon Dugan-Rocha, Lucinda A Fulton, Ramatu Ayiesha Gabisi, Toni T Garner, Jennifer Godfrey, Alicia C Hawes, Judith Hernandez, Sandra Hines, Michael Holder, Jennifer Hume, Shalini N Jhangiani, Vandita Joshi, Ziad Mohid Khan, Ewen F Kirkness, Andrew Cree, R Gerald Fowler, Sandra Lee, Lora R Lewis, Rasmus Nielsen, Rhesus Macaque Genome Sequencing and Analysis Consortium

Microbiology

924 Citationer (Scopus)

Abstract

Udgivelsesdato: 2007-Apr-13

Originalsprog	Engelsk
Tidsskrift	Science
Vol/bind	316
Udgave nummer	5822
Sider (fra-til)	222-34
Antal sider	12
ISSN	0036-8075
DOI	https://doi.org/10.1126/science.1139247
Status	Udgivet - 2007

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10.1126/science.1139247

Citationsformater

Gibbs, R. A., Rogers, J., Katze, M. G., Bumgarner, R., Weinstock, G. M., Mardis, E. R., Remington, K. A., Strausberg, R. L., Venter, J. C., Wilson, R. K., Batzer, M. A., Bustamante, C. D., Eichler, E. E., Hahn, M. W., Hardison, R. C., Makova, K. D., Miller, W., Milosavljevic, A., Palermo, R. E., ... Rhesus Macaque Genome Sequencing and Analysis Consortium (2007). Evolutionary and biomedical insights from the rhesus macaque genome. Science, 316(5822), 222-34. https://doi.org/10.1126/science.1139247

Gibbs, RA, Rogers, J, Katze, MG, Bumgarner, R, Weinstock, GM, Mardis, ER, Remington, KA, Strausberg, RL, Venter, JC, Wilson, RK, Batzer, MA, Bustamante, CD, Eichler, EE, Hahn, MW, Hardison, RC, Makova, KD, Miller, W, Milosavljevic, A, Palermo, RE, Siepel, A, Sikela, JM, Attaway, T, Bell, S, Bernard, KE, Buhay, CJ, Chandrabose, MN, Dao, M, Davis, C, Delehaunty, KD, Ding, Y, Dinh, HH, Dugan-Rocha, S, Fulton, LA, Gabisi, RA, Garner, TT, Godfrey, J, Hawes, AC, Hernandez, J, Hines, S, Holder, M, Hume, J, Jhangiani, SN, Joshi, V, Khan, ZM, Kirkness, EF, Cree, A, Fowler, RG, Lee, S, Lewis, LR, Nielsen, R & Rhesus Macaque Genome Sequencing and Analysis Consortium 2007, 'Evolutionary and biomedical insights from the rhesus macaque genome', Science, bind 316, nr. 5822, s. 222-34. https://doi.org/10.1126/science.1139247

@article{fda84ef0194411deb43e000ea68e967b,

title = "Evolutionary and biomedical insights from the rhesus macaque genome",

abstract = "The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and physiologically similar to humans, rhesus monkeys are the most widely used nonhuman primate in basic and applied biomedical research. We determined the genome sequence of an Indian-origin Macaca mulatta female and compared the data with chimpanzees and humans to reveal the structure of ancestral primate genomes and to identify evidence for positive selection and lineage-specific expansions and contractions of gene families. A comparison of sequences from individual animals was used to investigate their underlying genetic diversity. The complete description of the macaque genome blueprint enhances the utility of this animal model for biomedical research and improves our understanding of the basic biology of the species.",

author = "Gibbs, {Richard A} and Jeffrey Rogers and Katze, {Michael G} and Roger Bumgarner and Weinstock, {George M} and Mardis, {Elaine R} and Remington, {Karin A} and Strausberg, {Robert L} and Venter, {J Craig} and Wilson, {Richard K} and Batzer, {Mark A} and Bustamante, {Carlos D} and Eichler, {Evan E} and Hahn, {Matthew W} and Hardison, {Ross C} and Makova, {Kateryna D} and Webb Miller and Aleksandar Milosavljevic and Palermo, {Robert E} and Adam Siepel and Sikela, {James M} and Tony Attaway and Stephanie Bell and Bernard, {Kelly E} and Buhay, {Christian J} and Chandrabose, {Mimi N} and Marvin Dao and Clay Davis and Delehaunty, {Kimberly D} and Yan Ding and Dinh, {Huyen H} and Shannon Dugan-Rocha and Fulton, {Lucinda A} and Gabisi, {Ramatu Ayiesha} and Garner, {Toni T} and Jennifer Godfrey and Hawes, {Alicia C} and Judith Hernandez and Sandra Hines and Michael Holder and Jennifer Hume and Jhangiani, {Shalini N} and Vandita Joshi and Khan, {Ziad Mohid} and Kirkness, {Ewen F} and Andrew Cree and Fowler, {R Gerald} and Sandra Lee and Lewis, {Lora R} and Rasmus Nielsen and {Rhesus Macaque Genome Sequencing and Analysis Consortium}",

note = "Keywords: Animals; Biomedical Research; Evolution, Molecular; Female; Gene Duplication; Gene Rearrangement; Genetic Diseases, Inborn; Genetic Variation; Genome; Humans; Macaca mulatta; Male; Multigene Family; Mutation; Pan troglodytes; Sequence Analysis, DNA; Species Specificity",

year = "2007",

doi = "10.1126/science.1139247",

language = "English",

volume = "316",

pages = "222--34",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "5822",

}

TY - JOUR

T1 - Evolutionary and biomedical insights from the rhesus macaque genome

AU - Gibbs, Richard A

AU - Rogers, Jeffrey

AU - Katze, Michael G

AU - Bumgarner, Roger

AU - Weinstock, George M

AU - Mardis, Elaine R

AU - Remington, Karin A

AU - Strausberg, Robert L

AU - Venter, J Craig

AU - Wilson, Richard K

AU - Batzer, Mark A

AU - Bustamante, Carlos D

AU - Eichler, Evan E

AU - Hahn, Matthew W

AU - Hardison, Ross C

AU - Makova, Kateryna D

AU - Miller, Webb

AU - Milosavljevic, Aleksandar

AU - Palermo, Robert E

AU - Siepel, Adam

AU - Sikela, James M

AU - Attaway, Tony

AU - Bell, Stephanie

AU - Bernard, Kelly E

AU - Buhay, Christian J

AU - Chandrabose, Mimi N

AU - Dao, Marvin

AU - Davis, Clay

AU - Delehaunty, Kimberly D

AU - Ding, Yan

AU - Dinh, Huyen H

AU - Dugan-Rocha, Shannon

AU - Fulton, Lucinda A

AU - Gabisi, Ramatu Ayiesha

AU - Garner, Toni T

AU - Godfrey, Jennifer

AU - Hawes, Alicia C

AU - Hernandez, Judith

AU - Hines, Sandra

AU - Holder, Michael

AU - Hume, Jennifer

AU - Jhangiani, Shalini N

AU - Joshi, Vandita

AU - Khan, Ziad Mohid

AU - Kirkness, Ewen F

AU - Cree, Andrew

AU - Fowler, R Gerald

AU - Lee, Sandra

AU - Lewis, Lora R

AU - Nielsen, Rasmus

AU - Rhesus Macaque Genome Sequencing and Analysis Consortium

N1 - Keywords: Animals; Biomedical Research; Evolution, Molecular; Female; Gene Duplication; Gene Rearrangement; Genetic Diseases, Inborn; Genetic Variation; Genome; Humans; Macaca mulatta; Male; Multigene Family; Mutation; Pan troglodytes; Sequence Analysis, DNA; Species Specificity

PY - 2007

Y1 - 2007

N2 - The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and physiologically similar to humans, rhesus monkeys are the most widely used nonhuman primate in basic and applied biomedical research. We determined the genome sequence of an Indian-origin Macaca mulatta female and compared the data with chimpanzees and humans to reveal the structure of ancestral primate genomes and to identify evidence for positive selection and lineage-specific expansions and contractions of gene families. A comparison of sequences from individual animals was used to investigate their underlying genetic diversity. The complete description of the macaque genome blueprint enhances the utility of this animal model for biomedical research and improves our understanding of the basic biology of the species.

AB - The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and physiologically similar to humans, rhesus monkeys are the most widely used nonhuman primate in basic and applied biomedical research. We determined the genome sequence of an Indian-origin Macaca mulatta female and compared the data with chimpanzees and humans to reveal the structure of ancestral primate genomes and to identify evidence for positive selection and lineage-specific expansions and contractions of gene families. A comparison of sequences from individual animals was used to investigate their underlying genetic diversity. The complete description of the macaque genome blueprint enhances the utility of this animal model for biomedical research and improves our understanding of the basic biology of the species.

U2 - 10.1126/science.1139247

DO - 10.1126/science.1139247

M3 - Journal article

C2 - 17431167

SN - 0036-8075

VL - 316

SP - 222

EP - 234

JO - Science

JF - Science

IS - 5822

ER -

Evolutionary and biomedical insights from the rhesus macaque genome

Abstract

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