EULAR Sjögren's syndrome disease activity index (ESSDAI): a user guide

Raphaèle Seror; Simon J Bowman; Pilar Brito-Zeron; Elke Theander; Hendrika Bootsma; Athanasios Tzioufas; Jacques-Eric Gottenberg; Manel Ramos-Casals; Thomas Dörner; Philippe Ravaud; Claudio Vitali; Xavier Mariette; Karsten Asmussen; Soren Jacobsen; Elena Bartoloni; Roberto Gerli; Johannes Wj Bijlsma; Aike A Kruize; Stefano Bombardieri; Arthur Bookman; Cees Kallenberg; Petra Meiners; Johan G Brun; Roland Jonsson; Roberto Caporali; Steven Carsons; Salvatore De Vita; Nicoletta Del Papa; Valerie Devauchelle; Alain Saraux; Anne-Laure Fauchais; Jean Sibilia; Eric Hachulla; Gabor Illei; David Isenberg; Adrian Jones; Menelaos Manoussakis; Thomas Mandl; Lennart Jacobsson; Frederic Demoulins; Carlomaurizio Montecucco; Wan-Fai Ng; Sumusu Nishiyama; Roald Omdal; Ann Parke; Sonja Praprotnik; Matjia Tomsic; Elizabeth Price; Hal Scofield; Kathy L Sivils; Josef Smolen; Roser Solans Laqué; Serge Steinfeld; Nurhan Sutcliffe; Takayuki Sumida; Guido Valesini; Valeria Valim; Frederick B Vivino; Cristina Vollenweider

doi:10.1136/rmdopen-2014-000022

EULAR Sjögren's syndrome disease activity index (ESSDAI): a user guide

Raphaèle Seror, Simon J Bowman, Pilar Brito-Zeron, Elke Theander, Hendrika Bootsma, Athanasios Tzioufas, Jacques-Eric Gottenberg, Manel Ramos-Casals, Thomas Dörner, Philippe Ravaud, Claudio Vitali, Xavier Mariette, Karsten Asmussen, Soren Jacobsen, Elena Bartoloni, Roberto Gerli, Johannes Wj Bijlsma, Aike A Kruize, Stefano Bombardieri, Arthur BookmanCees Kallenberg, Petra Meiners, Johan G Brun, Roland Jonsson, Roberto Caporali, Steven Carsons, Salvatore De Vita, Nicoletta Del Papa, Valerie Devauchelle, Alain Saraux, Anne-Laure Fauchais, Jean Sibilia, Eric Hachulla, Gabor Illei, David Isenberg, Adrian Jones, Menelaos Manoussakis, Thomas Mandl, Lennart Jacobsson, Frederic Demoulins, Carlomaurizio Montecucco, Wan-Fai Ng, Sumusu Nishiyama, Roald Omdal, Ann Parke, Sonja Praprotnik, Matjia Tomsic, Elizabeth Price, Hal Scofield, Kathy L Sivils, Josef Smolen, Roser Solans Laqué, Serge Steinfeld, Nurhan Sutcliffe, Takayuki Sumida, Guido Valesini, Valeria Valim, Frederick B Vivino, Cristina Vollenweider

Institut for Klinisk Medicin

127 Citationer (Scopus)

Abstract

The EULAR Sjögren's syndrome (SS) disease activity index (ESSDAI) is a systemic disease activity index that was designed to measure disease activity in patients with primary SS. With the growing use of the ESSDAI, some domains appear to be more challenging to rate than others. The ESSDAI is now in use as a gold standard to measure disease activity in clinical studies, and as an outcome measure, even a primary outcome measure, in current randomised clinical trials. Therefore, ensuring an accurate and reproducible rating of each domain, by providing a more detailed definition of each domain, has emerged as an urgent need. The purpose of the present article is to provide a user guide for the ESSDAI. This guide provides definitions and precisions on the rating of each domain. It also includes some minor improvement of the score to integrate advance in knowledge of disease manifestations. This user guide may help clinicians to use the ESSDAI, and increase the reliability of rating and consequently of the ability to detect true changes over time. This better appraisal of ESSDAI items, along with the recent definition of disease activity levels and minimal clinically important change, will improve the assessment of patients with primary SS and facilitate the demonstration of effectiveness of treatment for patients with primary SS.

Originalsprog	Engelsk
Artikelnummer	e000022
Tidsskrift	RMD Open: Rheumatic & Musculoskeletal Diseases
Vol/bind	1
Udgave nummer	1
Sider (fra-til)	1-9
Antal sider	9
ISSN	2056-5933
DOI	https://doi.org/10.1136/rmdopen-2014-000022
Status	Udgivet - jan. 2015

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10.1136/rmdopen-2014-000022Licens: CC BY-NC

Citationsformater

Seror, R., Bowman, S. J., Brito-Zeron, P., Theander, E., Bootsma, H., Tzioufas, A., Gottenberg, J-E., Ramos-Casals, M., Dörner, T., Ravaud, P., Vitali, C., Mariette, X., Asmussen, K., Jacobsen, S., Bartoloni, E., Gerli, R., Bijlsma, J. W., Kruize, A. A., Bombardieri, S., ... Vollenweider, C. (2015). EULAR Sjögren's syndrome disease activity index (ESSDAI): a user guide. RMD Open: Rheumatic & Musculoskeletal Diseases, 1(1), 1-9. [e000022]. https://doi.org/10.1136/rmdopen-2014-000022

Seror, R, Bowman, SJ, Brito-Zeron, P, Theander, E, Bootsma, H, Tzioufas, A, Gottenberg, J-E, Ramos-Casals, M, Dörner, T, Ravaud, P, Vitali, C, Mariette, X, Asmussen, K, Jacobsen, S, Bartoloni, E, Gerli, R, Bijlsma, JW, Kruize, AA, Bombardieri, S, Bookman, A, Kallenberg, C, Meiners, P, Brun, JG, Jonsson, R, Caporali, R, Carsons, S, De Vita, S, Del Papa, N, Devauchelle, V, Saraux, A, Fauchais, A-L, Sibilia, J, Hachulla, E, Illei, G, Isenberg, D, Jones, A, Manoussakis, M, Mandl, T, Jacobsson, L, Demoulins, F, Montecucco, C, Ng, W-F, Nishiyama, S, Omdal, R, Parke, A, Praprotnik, S, Tomsic, M, Price, E, Scofield, H, L Sivils, K, Smolen, J, Laqué, RS, Steinfeld, S, Sutcliffe, N, Sumida, T, Valesini, G, Valim, V, Vivino, FB & Vollenweider, C 2015, 'EULAR Sjögren's syndrome disease activity index (ESSDAI): a user guide', RMD Open: Rheumatic & Musculoskeletal Diseases, bind 1, nr. 1, e000022, s. 1-9. https://doi.org/10.1136/rmdopen-2014-000022

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abstract = "The EULAR Sj{\"o}gren's syndrome (SS) disease activity index (ESSDAI) is a systemic disease activity index that was designed to measure disease activity in patients with primary SS. With the growing use of the ESSDAI, some domains appear to be more challenging to rate than others. The ESSDAI is now in use as a gold standard to measure disease activity in clinical studies, and as an outcome measure, even a primary outcome measure, in current randomised clinical trials. Therefore, ensuring an accurate and reproducible rating of each domain, by providing a more detailed definition of each domain, has emerged as an urgent need. The purpose of the present article is to provide a user guide for the ESSDAI. This guide provides definitions and precisions on the rating of each domain. It also includes some minor improvement of the score to integrate advance in knowledge of disease manifestations. This user guide may help clinicians to use the ESSDAI, and increase the reliability of rating and consequently of the ability to detect true changes over time. This better appraisal of ESSDAI items, along with the recent definition of disease activity levels and minimal clinically important change, will improve the assessment of patients with primary SS and facilitate the demonstration of effectiveness of treatment for patients with primary SS.",

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AU - Seror, Raphaèle

AU - Bowman, Simon J

AU - Brito-Zeron, Pilar

AU - Theander, Elke

AU - Bootsma, Hendrika

AU - Tzioufas, Athanasios

AU - Gottenberg, Jacques-Eric

AU - Ramos-Casals, Manel

AU - Dörner, Thomas

AU - Ravaud, Philippe

AU - Vitali, Claudio

AU - Mariette, Xavier

AU - Asmussen, Karsten

AU - Jacobsen, Soren

AU - Bartoloni, Elena

AU - Gerli, Roberto

AU - Bijlsma, Johannes Wj

AU - Kruize, Aike A

AU - Bombardieri, Stefano

AU - Bookman, Arthur

AU - Kallenberg, Cees

AU - Meiners, Petra

AU - Brun, Johan G

AU - Jonsson, Roland

AU - Caporali, Roberto

AU - Carsons, Steven

AU - De Vita, Salvatore

AU - Del Papa, Nicoletta

AU - Devauchelle, Valerie

AU - Saraux, Alain

AU - Fauchais, Anne-Laure

AU - Sibilia, Jean

AU - Hachulla, Eric

AU - Illei, Gabor

AU - Isenberg, David

AU - Jones, Adrian

AU - Manoussakis, Menelaos

AU - Mandl, Thomas

AU - Jacobsson, Lennart

AU - Demoulins, Frederic

AU - Montecucco, Carlomaurizio

AU - Ng, Wan-Fai

AU - Nishiyama, Sumusu

AU - Omdal, Roald

AU - Parke, Ann

AU - Praprotnik, Sonja

AU - Tomsic, Matjia

AU - Price, Elizabeth

AU - Scofield, Hal

AU - L Sivils, Kathy

AU - Smolen, Josef

AU - Laqué, Roser Solans

AU - Steinfeld, Serge

AU - Sutcliffe, Nurhan

AU - Sumida, Takayuki

AU - Valesini, Guido

AU - Valim, Valeria

AU - Vivino, Frederick B

AU - Vollenweider, Cristina

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U2 - 10.1136/rmdopen-2014-000022

DO - 10.1136/rmdopen-2014-000022

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ER -

EULAR Sjögren's syndrome disease activity index (ESSDAI): a user guide

Abstract

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