ERK2 Suppresses Self-Renewal Capacity of Embryonic Stem Cells, but Is Not Required for Multi-Lineage Commitment

Keyphrases

• ERK2 100%
• Embryonic Stem Cells 100%
• Self-renewal 100%
• Lineage Commitment 100%
• Multilineage 100%
• Nanog 42%
• ERK1 28%
• Phosphorylation 28%
• Pluripotency Genes 28%
• Induction Conditions 14%
• TBX3 14%
• ERK Activity 14%
• Immediate-early Gene 14%
• Neural Induction 14%
• Gene Expression 14%
• Three Germ Layers 14%
• Genetic Ablation 14%
• Isozymes 14%
• Transgenic Expression 14%
• Transgenic 14%
• Functional Redundancy 14%
• ERK Pathway 14%
• Gene Induction 14%
• Germ Layer Specification 14%
• Embryoid Body 14%
• Stem Cell Self-renewal 14%
• Nave 14%
• Mouse Embryonic Stem Cells (mESCs) 14%
• P90RSK 14%
• Pluripotency 14%
• Lineage Specification 14%
• Hyperphosphorylation 14%
• Colony Formation Assay 14%

Biochemistry, Genetics and Molecular Biology

• Embryonic Stem Cell 100%
• Nanog 50%
• Germ Layer 33%
• Transgenics 33%
• Hyperphosphorylation 16%
• Isoenzyme 16%
• Gene Expression 16%
• Gene Induction 16%
• Genetic Ablation 16%
• Embryoid Body 16%
• Immediate Early Gene 16%
• Stem Cell Self-Renewal 16%