Endoscopic retrograde cholangiopancreatography causes reduced myocardial blood flow

TY - JOUR

T1 - Endoscopic retrograde cholangiopancreatography causes reduced myocardial blood flow

AU - Christensen, M

AU - Hendel, H W

AU - Rasmussen, V

AU - Højgaard, L

AU - Schulze, S

AU - Rosenberg, J

PY - 2002/10

Y1 - 2002/10

N2 - BACKGROUND AND STUDY AIMS: Previous studies have shown that up to 50% of healthy patients may develop ST-segment changes during upper gastrointestinal endoscopy. The aim of the study was to evaluate myocardial blood flow in patients during endoscopic retrograde cholangiopancreatography (ERCP).PATIENTS AND METHODS: 11 patients scheduled for ERCP were monitored with a Holter tape recorder and underwent myocardial perfusion scintigraphies, to evaluate myocardial perfusion at rest and during ERCP.RESULTS: Ten patients completed the study. Eight patients had no sign of myocardial ischemia with either of the two methods, while two patients developed signs of ischemia during ERCP with both the Holter tape recording and on myocardial scintigraphy (P = 0.02).CONCLUSIONS: Patients undergoing ERCP may develop true myocardial ischemia with reduced myocardial blood flow. Although this is a small-scale study, these findings strongly support the use of alternative methods for diagnostic evaluation of the pancreatic duct and biliary tree.

AB - BACKGROUND AND STUDY AIMS: Previous studies have shown that up to 50% of healthy patients may develop ST-segment changes during upper gastrointestinal endoscopy. The aim of the study was to evaluate myocardial blood flow in patients during endoscopic retrograde cholangiopancreatography (ERCP).PATIENTS AND METHODS: 11 patients scheduled for ERCP were monitored with a Holter tape recorder and underwent myocardial perfusion scintigraphies, to evaluate myocardial perfusion at rest and during ERCP.RESULTS: Ten patients completed the study. Eight patients had no sign of myocardial ischemia with either of the two methods, while two patients developed signs of ischemia during ERCP with both the Holter tape recording and on myocardial scintigraphy (P = 0.02).CONCLUSIONS: Patients undergoing ERCP may develop true myocardial ischemia with reduced myocardial blood flow. Although this is a small-scale study, these findings strongly support the use of alternative methods for diagnostic evaluation of the pancreatic duct and biliary tree.

KW - Aged

KW - Cholangiopancreatography, Endoscopic Retrograde

KW - Coronary Circulation

KW - Electrocardiography, Ambulatory

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Myocardial Ischemia

KW - Pancreatic Ducts

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

U2 - 10.1055/s-2002-34270

DO - 10.1055/s-2002-34270

M3 - Journal article

C2 - 12244501

SN - 0013-726X

VL - 34

SP - 797

EP - 800

JO - Endoscopy

JF - Endoscopy

IS - 10

ER -